Objective To investigate the occurrence and influencing factors of facial numbness in patients with primary trigeminal neuralgia(PTN)after surgery,in order to provide a scientific basis for developing clinical measures to prevent and treat facial numbness.Methods A total of 214 patients with PTN who received microvascular decompression in our hospital from January 2018 to February 2023 were selected and divided into two groups according to whether facial numb-ness occurred 2 weeks after surgery.The clinical data of the two groups were compared and the related factors of facial numbness were analyzed by Logistic multivariate regression model.Results Two weeks after surgery,39 of 214 PTN pa-tients had facial numbness,the incidence was 18.22%(39/214).There were statistically significant differences in neuro-vascular indentation,decompression degree,compression degree and neuroendoscopy assistance between the two groups(P<0.05).Vascular indentation and compression degree(displacement)were risk factors for postoperative facial numb-ness in patients with PTN.The degree of decompression(sufficient)and the assistance of neuroendoscopy were protective factors for postoperative facial numbness in PTN patients.Conclusion The risk of facial numbness after microvascular de-compression in patients with PTN is higher,which is mainly related to the vascular indentation on the nerve,the degree of compression,the degree of decompression,the assistance of neuroendoscopy and other factors.In clinical diagnosis and treat-ment,early diagnosis and early operation should be carried out to minimize the operation time and reduce the risk of facial numbness after surgery.