摘要
目的 分析影响维持性血液透析(MHD)患者继发透析相关性高血压的相关因素,并探讨相应防治措施.方法 选取2020年1月-2022年12月间我院收治的MHD患者76例,根据有无继发透析相关性高血压将其分为高血压组39例,对照组37例,分析两组基线资料,采用多因素Logistic回归分析影响MHD患者继发透析相关性高血压的相关因素.结果 单因素分析显示,MHD患者继发透析相关性高血压与MHD病程、体重变化、营养状态、EPO用量有关;采用多因素Logistic回归分析显示,MHD病程＞5年[OR=3.827,95％CI(1.352,10.835)]、体重变化＞5kg[OR=6.366,95％CI(2.071,19.572)]、营养不良[OR=3.543,95％CI(1.424,8.815)]、EPO 用量≥3000U/周[OR=4.216,95％CI(1.446,12.295)]是MHD患者继发透析相关性高血压的独立危险因素.结论 MHD病程、体重变化、营养不良、EPO用量是MHD患者继发透析相关性高血压的独立危险因素,可采取早期筛查、营养干预、用药管理、体重监测等方式进行防护.
Abstract
Objective To analyze the relevant factors affecting secondary dialysis related hypertension in maintenance hemodialysis(MHD)patients and explore corresponding prevention and treatment measures.Methods 76 MHD patients admitted to our hospital from January 2020 to December 2022 were selected.They were divided into a hypertension group of 39 cases and a control group of 37 cases based on the occurrence of secondary dialysis related hypertension.The baseline data of the two groups were analyzed,and multivariate logistic regression analysis was used to analyze the relevant factors af-fecting secondary dialysis related hypertension in MHD patients.Results Univariate analysis showed that secondary dialy-sis related hypertension in MHD patients was related to the course of MHD,weight change,nutritional status,and EPO dos-age;Using multivariate logistic regression analysis,it was found that the duration of MHD＞5 years[OR=3.827,95％CI(1.352,10.835)],weight change＞5 kg[OR=6.366,95％CI(2.071,19.572)],malnutrition[OR=3.543,95％CI(1.424,8.815)],and EPO dosage≥3000U/week[OR=4.216,95％CI(1.446,12.295)]are independent risk factors for secondary dialysis related hypertension in MHD patients.Conclusion The course of MHD,weight changes,malnutri-tion,and EPO dosage are independent risk factors for secondary dialysis related hypertension in MHD patients.Early screen-ing,nutritional intervention,medication management,and weight monitoring can be taken for protection.
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