大肠癌凝血功能变化与临床证型相关性探讨
The Exploration of the Relationship Between the Change of Coagulation Function and the TCM Syndrome type
李累 1贾彦焘2
作者信息
- 1. 天津中医药大学,天津,300193
- 2. 天津中医药大学第一附属医院肿瘤科,天津,300193
- 折叠
摘要
目的:探讨大肠癌患者凝血功能、血小板指标的变化与中医证型的关系及临床意义.方法:测定120例健康体检者和135例大肠癌患者的PT、APTT、TT、Fib含量水平,并计数PLT,分为5种证型进行比较.结果:135例大肠癌患者中73例(54.07%)Fib升高,64例(47.41%)PLT升高,55例(40.74%)AFTT降低,47例(34.81%)PT降低,48例(35.56%)TT降低,血瘀型与其他证型有显著差异(P<0.05),不同证型大肠癌均较健康人血液黏稠度升高(P<0.05).结论:大肠癌患者血液处于高凝状态,有潜在血栓形成的可能,预后欠佳,凝血功能变化程度与中医证型有一定相关性.
Abstract
Objective:To explore the relationship between the coagulation function、the level change of platelets and the TCM syndrome type for the colorectal carcinoma. Methods :135 patients suffering from colorectal carcinoma and 120 normal adult were enrolled, prothombin time ( PT ), activated paritial thromboplastin time (APTF), thrombin time ( TT ), fibrinogen ( Fib ), and platelets were detected in all patients and control group, and all the patients were divided into 5 groups to make a comparison according to the TCM Syndrome type. Results: The number of increased level were 73 ( 54. 07 ％ ) for Fib,64 (47.41％) for PLTo The number of decreased level were 55 (40. 74％ ) for APTT,47 ( 34. 81％ ) for PT,48 ( 35.56％ ) for TT during all the 135 patients o There were a significant difference between the blood -stasis syndrome type and other syndrome type(P ＜ 0. 05 ), all the patients of the 5 syndrome express a higher level of blood viscosity. Conclusion:The are abnormal level of Fib,PLT,PT,APTT with colorectal carcinoma,Their changes are partely related with the TCM syndrome type.
关键词
大肠癌/凝血功能/中医证型Key words
colorectal carcinoma/coagulation function/TCM syndrome type引用本文复制引用
出版年
2011
国家科技期刊平台
NSTL
维普
万方数据