Analysis of TCM Syndrome Elements in 242 Patients with Pulmonary Nodules
Objective To analyze the distribution characteristics and combination rules of syndrome elements of disease loca-tion and disease nature in patients with pulmonary nodule,explore the correlation between syndrome elements and nodule attrib-utes,and provide reference for clinical diagnosis and treatment.Methods The clinical data of 242 patients with pulmonary nodule was collected,including general data,imaging data and syndrome data.Frequency statistics and cluster analysis were carried out to extract the distribution characteristics and combination rules of syndrome elements,and further analyze the correlation between syndrome elements and nodule attributes.Results The TCM symptoms and syndromes of 98.8％of the patients with pulmonary nodule were collected,of which 95.4％could be diagnosed as corresponding syndrome elements.A total of 35 syndrome elements were extracted,including 21 syndrome elements of disease nature and 14 syndrome elements of disease location.The high-fre-quency syndrome elements of disease nature(frequency＞10％)were damp(48.5％),phlegm(47.3％),Yang deficiency(42.7％),Yin deficiency(42.3％),Qi deficiency(39.3％),Qi stagnation(29.7％),blood deficiency(27.2％),blood stasis(18.4％)and cold(17.6％).The high-frequency syndrome elements of disease location were lung(57.3％),liver(21.3％),kidney(18.8％),heart(15.9％),exterior(14.2％)and spleen(10.9％).Cluster analysis of high-frequency syndrome ele-ments showed four syndrome element combinations:Qi deficiency,Yang deficiency and blood deficiency;heart,blood stasis,liver,Qi stagnation,kidney deficiency and Yin deficiency;spleen,dampness;lung,phlegm,exterior and cold.By analyzing the correla-tion between syndrome factors and nodules,it was found that phlegm syndrome factors were significantly different among nodules of different properties,and there was no significant correlation between syndrome factors and nodule diameter.Conclusion The main disease location of pulmonary nodules is in the lung,and dampness and phlegm are the main pathological factors.The four syndrome el-ement combinations are obtained,which provide a reference for the precise diagnosis and treatment of pulmonary nodules in TCM.
万方数据
维普
