Clinical Study on Jianggui Yiying Decoction(姜桂益瘿汤)Assisting Western Medicine in Treatment of Hashimoto's Thyroiditis with Spleen-Kidney Yang Deficiency
Objective To analyze the effect of Jianggui Yiying Decoction(姜桂益瘿汤)on Hashimoto's thyroiditis with spleen-kidney Yang deficiency.Methods A hundred and forty-five patients with Hashimoto's thyroiditis admitted to Qinhuang-dao Hospital of Traditional Chinese Medicine were divided into the control group(72 cases)and the research group(73 cases).The grouping method was random number table method,and the selection time was from February 2022 to April 2023.The control group was treated with western medicine,and the research group was treated with Jianggui Yiying Decoction on the basis of the control group.The two groups were treated continuously for 12 weeks.The clinical efficacy after treatment and the occurrence of adverse reactions during treatment,the scores of TCM symptoms and signs,thyroid volume and isthmus thickness,serum thyroid stimulating hormone(TSH),thyroglobulin antibody(TGAb)and thyroid peroxidase antibody(TPOAb)before and after treatment were compared between the two groups.Results After treatment,the total effective rate of the research group was higher than that of the control group.After treatment,compared with those before treatment,the scores of neck infarction,neck swelling,anorexia,constipation,facial edema,mental fatigue,fear of cold,increased body mass index,serum levels of TSH,TGAb and TPOAb,volume of left and right thyroid lobes and isthmus thickness of the two groups decreased,and the results of the research group were lower than those of the control group(P＜0.05).During treatment,there were no obvious adverse reactions in both groups.Conclusion The treatment of Hashimoto's thyroiditis of spleen-kidney Yang deficiency with Jianggui Yiying Decoction is helpful to relieve the clinical symptoms and signs of patients,regulate the expressions of disease-related serum indicators,improve the thyroid vol-ume and isthmus thickness,and improve the clinical efficacy,with high safety.
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