A Study on the Medication Rules for the Treatment of Male Infertility in the Integrated Medical Records of Ancient and Modern Books Based on Data Mining
Objective To explore the medication rules for the treatment of male infertility(MI)in the"Complete Collection of Ancient and Modern Books and Medical Records",and to provide clinical services.Methods Retrieve the prescriptions for trea-ting MI from the Complete Records of the Integrated Medical Department of Ancient and Modern Books,and input the drugs ob-tained into the Traditional Chinese Medicine Inheritance Calculation Platform(V3.5)software.Use the data analysis methods in the system to perform statistical analysis,correlation analysis,and cluster analysis on the drugs.Results77prescriptions for the treatment of MI were included in the Complete Collection of Ancient and Modern Books by the Medical Department,andatotal of 192 traditional Chinese medicines were used.The analysis of the four gases shows that the most frequently used is warm drugs;The analysis of five flavors shows that the most frequently used is the sweet flavored medication;According to the analysis of me-ridians,the most frequently used drugs are those that belong to the kidney meridian;Analysis of traditional Chinese medicine shows that the top10 most frequently used Chinese medicines are Rehmanniaglutinosa,Poriacocos,Angelicasinensis,honey,Achyranthesbidentata,ginseng,Cistanchedeserticola,Gojiberries,Dodderseed,and Eucommiaulmoides;The efficacy analysis shows that the most commonly used Chinese medicine is tonifying deficiency,followed by astringent Chinese medicine;Setasupport score of ≥ 20 and aconfidence level of 0.7.Frequency analysis shows that the commonly used drug combinations are"Rehmannia glutinosa Poria","Rehmannia glutinosa Angelica","Rehmanniaglutinosahoney",and"Rehmannia glutinosa ginseng";The com-monly used medication rules are"Morinda officinalis→Cistanched eserticola","Ginseng→ Rehmanniaglutinosa","Honey→Reh-manniaglutinosa",and"Cistanchedeserticola→Morindaofficinalis";Obtain 3 new songs.Conclusion The"Complete Collection of Ancientand Modern Books from the Medical Department"emphasizes the treatment of MI by nourishing the kidney and essence,nourishingyin and blood,using pure and peaceful medication,warming butnotrestless,fixingbutnot astringent,and combining tonify-ing and purging.It has high practical value for contemporary clinical treatment of MI.
Integrated medical records of ancient and modern booksMalein fertilityData miningMedication patterns