首页|针药结合治疗子宫腺肌病气虚血瘀型疗效及对患者卵巢功能、免疫功能的影响

针药结合治疗子宫腺肌病气虚血瘀型疗效及对患者卵巢功能、免疫功能的影响

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目的 探讨针药结合治疗子宫腺肌病(气虚血瘀型)疗效及对患者卵巢功能、免疫功能影响.方法 纳入63例子宫腺肌病(气虚血瘀型)患者(2021年9月-2022年8月收治)进行实验研究,采取随机数字表法将纳入患者分为对照组(31例)、观察组(32例),对照组患者采取地诺孕素治疗,观察组患者在对照组治疗基础上结合针药治疗,观察各组患者数据:疗效、治疗前后中医证候积分(经行腹痛、经期延长、经行量多、面色淡而晦暗、肛门坠胀不适等)变化、痛经严重程度(VAS)变化 及月经量变化,测定促卵泡生成素(FSH)、促黄体生成素(LH)、雌二醇(E2)水平观察各组卵巢功能,测定免疫球蛋白A(IgA)、免疫球蛋白G(IgG)、免疫球蛋白M(IgM)评估患者免疫功能、不良反应.结果 对照组与观察组疗效分别为77.42%、96.88%,后者更高,P<0.05;各组患者治疗前中医证候积分(经行腹痛、经期延长、经行量多、面色淡而晦暗、肛门坠胀不适等)、VAS评分与月经量、卵巢功能指标(FSH、LH、E2)、免疫功能指标(IgA、IgG、IgM)比较,P>0.05,治疗后各组患者中医证候积分、VAS评分与月经量、卵巢功能指标与免疫功能指标均改善,且观察组患者治疗后中医证候积分、VAS评分与月经量、卵巢功能指标与免疫功能指标均优于对照组,P<0.05;各组不良反应率均较低,P>0.05.结论 针药结合治疗子宫腺肌病(气虚血瘀型)疗效较好,患者临床病症、卵巢功能与免疫功能均改善,治疗不良反应少,值得应用.
Observation on the Curative Effect of Acupuncture and Medicine Combined Treatment of Adenomyopathy(Qi Deficiency and Blood Stasis Type)and its Influence on Ovarian Function and Immune Function of Patients
Objective To investigate the effect of acupuncture and medicine combined treatment of adenomyopathy(Qi-defi-ciency and blood-stasis type)and its influence on ovarian function and immune function.Methods Sixty-three patients with ad-enomyopathy(qi deficiency and blood stasis type)(admitted from September 2021 to August 2022)were included in this experi-mental study.The patients were divided into control group(31 cases)and observation group(32 cases)by random number table method.The patients in the control group were treated with dinorgestrel,and the patients in the observation group were treated with acupuncture and drug on the basis of the treatment in the control group.Observation of patient data in each group:Curative effect,changes of TCM symptom scores(abdominal pain during menstruation,prolonged menstruation,heavy menstruation,pale and dull face,anal distension discomfort,etc.),changes of dysmenorrhea severity(VAS)and menstrual volume before and af-ter treatment,levels of follicle stimulating hormone(FSH),luteinizing hormone(LH)and estradiol(E2)were measured to ob-serve ovarian function in each group.Immunoglobulin A(IgA),immunoglobulin G(IgG)and immunoglobulin M(IgM)were determined to evaluate the immune function and adverse reactions.Results The curative effect of control group and observation group was 77.42%and 96.88%,respectively,the latter was higher(P<0.05).Before treatment,TCM syndrome scores(abdominal pain,prolonged menstrual period,heavy menstrual flow,pale and dark face,anal distension discomfort,etc.)and VAS scores were compared with menstrual volume,ovarian function indexes(FSH,LH,E2)and immune function indexes(IgA,IgG,IgM)in all groups,P>0.05.After treatment,TCM syndrome score,VAS score,menstrual volume,ovarian func-tion index and immune function index of all groups were improved,and observation group was better than control group,with P<0.05.The adverse reaction rate was lower in all groups(P>0.05).Conclusion The combination of acupuncture and medicine in the treatment of adenomyopathy(Qi-deficiency and blood-stasis type)has a good effect,and the clinical symptoms,ovari-an function and immune function of the patients are improved,and the treatment side effects are less,which is worthy of applica-tion.

adenomyopathyQi deficiency and blood stasis typeacupuncture medicineovarian functionimmune func-tionadverse reaction

吴天思、林晓华、秦玉璇、边文会、张春敏

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河北省中医院,河北 石家庄 050013

子宫腺肌病 气虚血瘀型 针药 卵巢功能 免疫功能 不良反应

2025

辽宁中医杂志
辽宁中医药大学,辽宁省中医药学会

辽宁中医杂志

北大核心
影响因子:0.815
ISSN:1000-1719
年,卷(期):2025.52(1)