负载型咪唑离子液体催化合成2,3-二氢喹唑啉-4(1H)-酮反应研究
Study on Synthesis of 2,3-dihydroquinazolin-4(1H)-one Catalyzed by Supported Imidazole Ionic Liquid
张葶 1戎启 2胡玉林1
作者信息
- 1. 安顺学院化学化工学院,贵州 安顺 561000
- 2. 三峡大学材料与化工学院,湖北 宜昌 443002
- 折叠
摘要
介绍了一种温和条件下催化合成2,3-二氢喹唑啉-4(1H)-酮的方法.该方法以负载型咪唑离子液体Al-MCM-41@ILCeCl4 为催化剂,在乙醇溶剂中,催化苯甲醛和2-氨基苯甲酰胺进行反应得到目标化合物,产率高达94%.Al-MCM-41@ILCeCl4催化剂具有制备方法简单、稳定性好、回收利用便捷等优点,符合绿色化学的发展方向,具有良好的应用前景.
Abstract
A type of Al-MCM-41 supported dual imidazolium ionic liquid Al-MCM-41@ILCe Cl4 has been synthesized and efficiently used as an catalyst in the one-pot synthesis of 2,3-dihydroquinazolin-4(1H)-one in the condensation of benzaldehyde and anthranilamide.It was shown that the high efficiency with high yield of 94%was achieved under mild conditions.Moreover,the catalyst was stable,very active,robust,and displayed good recyclability without significant loss of catalytic activity after five consecutive cycles during the process.The advantages of Al-MCM-41@ILCe Cl4 are simple preparation method,excellent biocom-patibility and convenient recycling,which meet the development direction of green chemistry and possess good industrial applica-tion prospects.
关键词
负载型离子液体/介孔Al-MCM-41/非均相催化/2,3-二氢喹唑啉-4(1H)-酮/可持续性Key words
Supported ionic liquids/Mesoporous Al-MCM-41/Heterogeneous catalysis/2,3-Dihydroquinazolin-4(1H)-one/Sustainability引用本文复制引用
基金项目
国家自然科学基金项目(22268023)
安顺学院大学生科研训练计划项目(asxysrt202320)
出版年
2024
国家科技期刊平台
NSTL
万方数据