Optimization of ultrasound—assisted deep eutectic solvent extraction of total navonoids from clitocybe odora muscaria
Ultrasound-assisted green deep eutectic solvent(DES)was used as the solvent to extract the total flavonoids of clitocybe odora muscaria.The effects of deep eutectic solvent of solid to liquid,water content and ultrasonic time on flavonoids of clitocybe odora muscaria and the extraction conditions were optimized o The results showed that the extraction efficiency of DES(choline chloride-urea)was higher than that of other DES,and the optimal extraction con-ditions were 1∶2 for choline chloride-urea,63%for water content,1∶39 for material-liquid ratio,and 56 min for ultrasonic time.The actual extraction rate of total flavonoids from agaricus blazei mushrooms under these conditions was 3.3%.
clitocybe odora muscariaflavonoidsdeep eutectic sol ventextraction