细胞外液黏度:细胞生物学中一个新的物理信号
Extracellular fluid viscosity:a new physical cue in cell biology
李英奇 1刘娜 2谢宁 1魏钊 3梁喜茹 4徐峰3
作者信息
- 1. Department of Gastroenterology,the Second Affiliated Hospital of Xi'an Jiaotong University,Xi'an 710049,China;Bioinspired Engineering and Biomechanics Center(BEBC),the Key Laboratory of Biomedical Information Engineering of Ministry of Education,School of Life Science and Technology,Xi'an Jiaotong University,Xi'an 710049,China
- 2. Bioinspired Engineering and Biomechanics Center(BEBC),the Key Laboratory of Biomedical Information Engineering of Ministry of Education,School of Life Science and Technology,Xi'an Jiaotong University,Xi'an 710049,China;Department of Gastroenterology Hainan General Hospital(Hainan Affiliated Hospital of Hainan Medical University),Haikou 570311,China
- 3. Bioinspired Engineering and Biomechanics Center(BEBC),the Key Laboratory of Biomedical Information Engineering of Ministry of Education,School of Life Science and Technology,Xi'an Jiaotong University,Xi'an 710049,China
- 4. Department of Gastroenterology,the Second Affiliated Hospital of Xi'an Jiaotong University,Xi'an 710049,China
- 折叠
摘要
细胞行为受到微环境中物理信号的调控,其中细胞外液(ECF)黏度作为一个重要的物理刺激,相关研究较少.近期研究表明:ECF黏度在调控与心血管相关疾病、炎症性疾病和癌症等多种疾病相关的细胞病理学过程中起关键作用.
Abstract
Cell behaviors are regulated by the physical cues in their microenvironment,where extracellular fluid(ECF)viscosity is an important yet relatively underexplored cue.Recent evidence indicates that ECF viscosity plays a critical role in regulating cellular processes with pathological relevance to various diseases,such as cardiovascular related diseases,inflammatory diseases,and cancer.
关键词
Mechanical microenvironment/Extracellular fluid viscosity/Human health/Cell behaviorKey words
Mechanical microenvironment/Extracellular fluid viscosity/Human health/Cell behavior引用本文复制引用
基金项目
National Natural Science Foundation of China(82303812)
出版年
2024
NETL
NSTL
万方数据