首页|全脑SIB-IMRT治疗EGFR野生型或耐药型肺腺癌脑转移瘤的疗效观察及护理体会

全脑SIB-IMRT治疗EGFR野生型或耐药型肺腺癌脑转移瘤的疗效观察及护理体会

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目的 探讨EGFR野生型或耐药型肺腺癌脑转移瘤的治疗及护理方法。方法 将46例EGFR野生型或耐药型肺腺癌脑转移瘤患者随机分为两组,各23例。两组均行全脑SIB-IMRT,观察组联合贝伐珠单抗;两组均采用循证护理干预。比较两组临床效果。结果 观察组临床疗效、瘤周水肿体积、健康指数及生活满意度得分改善程度均优于对照组(P<0。05)。结论 应用全脑SIB-IMRT联合贝伐珠单抗治疗EGFR野生型或耐药型肺腺癌脑转移瘤疗效肯定,安全性好。
CLINICAL EFFECT AND NURSING EXPERIENCE OF USING THE WHOLE BRAIN SIB-IMRT IN TREATING BRAIN METASTASES OF EGFR WILD-TYPE OR DRUG-RESISTANT LUNG ADENOCARCINOMA
Objective To explore the treatment and nursing of brain metastases of EGFR wild-type or drug-resistant lung adenocarcinoma.Methods 46 cases of brain metastases of EGFR wild-type or drug-re-sistant lung adenocarcinoma were randomly divided into two groups,with 23 cases in each group.Both groups were treated with the whole brain SIB-IMRT,while the observation group was treated with bevaci-zumab in addition.Both groups received evidence-based nursing intervention.The clinical effect of the two groups was compared.Results The clinical effect,peritumoral edema volume,health index and life satis-faction of the observation group were better than those of the control group(P<0.05).Conclusion The whole brain SIB-IMRT used with bevacizumab is effective and safe in treating brain metastases of EGFR wild-type or drug-resistant lung adenocarcinoma.

Lung adenocarcinomaBrain metastasesConcurrent thrust intensity modulated radio-therapyEvidence-based nursing

常瑛、刘京丽、刘莲花、黄丙俭

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临沂市肿瘤医院,山东临沂 276034

肺腺癌 脑转移 同期推量调强放疗 循证护理

2024

山东医学高等专科学校学报
山东医学高等专科学校

山东医学高等专科学校学报

影响因子:0.542
ISSN:1674-0947
年,卷(期):2024.46(4)
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