山东医学高等专科学校学报2024,Vol.46Issue(6) :7-10.DOI:10.3969/j.issn.1674-0947.2024.06.003

容积旋转调强放疗在局部晚期宫颈癌中的临床应用

THE CLINICAL APPLICATION OF VMAT IN LOCALLY ADVANCED CERVICAL CANCER

刘蓓蓓 李秀敏
山东医学高等专科学校学报2024,Vol.46Issue(6) :7-10.DOI:10.3969/j.issn.1674-0947.2024.06.003

容积旋转调强放疗在局部晚期宫颈癌中的临床应用

THE CLINICAL APPLICATION OF VMAT IN LOCALLY ADVANCED CERVICAL CANCER

刘蓓蓓 1李秀敏2
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作者信息

  • 1. 滨州医学院,山东 烟台 264003
  • 2. 临沂市肿瘤医院,山东 临沂 276000
  • 折叠

摘要

目的 观察VMAT在局部晚期宫颈癌中应用效果.方法 回顾性收集135例局部晚期宫颈癌患者临床资料,根据治疗方法的不同分为两组,VMAT 70例,IMRT 65例.计划靶体积剂量50.4Gy,比较两组靶区参数、危及器官剂量、治疗时间、近期疗效、急性不良反应及OS.结果 VMAT组CI值高于IMRT组(t=2.04,P=0.04),治疗时间短于IMRT组(t=30.57,P<0.01).两组其他指标比较均无统计学意义(P>0.05).结论 与IMRT相比,VMAT的适形度更好,可以明确缩短局部晚期宫颈癌患者的治疗时间.

Abstract

Objective To observe the application effect of VMAT in locally advanced cervical cancer.Methods The clinical data of 135 patients with locally advanced cervical cancer were retrospectively collect-ed and divided into two groups according to different treatment methods:70 VMAT cases and 65 IMRT cases.The target volume dose was planned to be 50.4Gy,and the target parameters,organ dose at risk,treatment time,short-term efficacy,acute adverse reactions and Overall Survival(OS)were compared be-tween the two groups.Results CI value in VMAT group was higher than that in IMRT group(t=2.04,P=0.04),and treatment time was shorter than that in IMRT group(t=30.57,P<0.001).There was no statistical significance in other indexes between the two groups(P>0.05).Conclusion Compared with IMRT,VMAT has better conformation and can clearly shorten the treatment time of locally advanced cer-vical cancer patients.

关键词

宫颈癌/容积旋转调强放疗/生存率/不良反应/靶区参数

Key words

Cervical cancer/Volume rotation intensity modulated radiotherapy/Survival rate/Adverse reactions/Target parameter

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出版年

2024
山东医学高等专科学校学报
山东医学高等专科学校

山东医学高等专科学校学报

影响因子:0.542
ISSN:1674-0947
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