Assumption that the slope sliding surface is a logarithmic spiral curve and the local instability mode a typical homogeneous slope,and by applying the upper limit theorem of limit analysis and calcu-lating the local stability of the slope before and after the pile respectively,an effective reinforcement area of the anti-slide pile was proposed.In consideration of the pile-soil interaction with the Ito theory,the seismic safety factor of anti-slide pile reinforcement slope and the minimum pile diameter or net distance between piles required by the known design safety factor,as well as the corresponding required re-sistance,the position of the resultant force of resistance and the pile length above the sliding surface were calculated.According to the resultant calculation and combining with the safety,economy and construc-tion difficulty of the project,a reasonable design pile position could be determined.The influence of seismic load and physical and mechanical parameters of rock and soil on the effective reinforcement area of the slope strengthened by mechanical parameters and the effective reinforcement area of the slope strengthened by anti-slide piles was analyzed through calculation case.