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维持性血液透析患者久坐行为发生风险列线图模型的构建

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目的 分析维持性血液透析患者的久坐行为发生的影响因素,并建立久坐行为发生风险的列线图模型.方法 便利抽样法选取 2024 年 1 月至 2024 年 6 月于芜湖市某三甲医院血液净化中心治疗的 579 例维持性血液透析患者作为研究对象.采用一般资料调查表、国际体力活动问卷、跌倒恐惧单条目问题法进行调查.结果 579 名患者中久坐行为的发生率为 68.0%(394/579).总计平均久坐时间为 378.57(341.43,428.57)min/d.logistic回归分析结果显示,年龄、全段甲状腺激素水平、跌倒恐惧、透析中低血压和营养风险指数是维持性血液透析患者久坐行为的影响因素,差异均有统计学意义(均P<0.05).基于5 项独立危险因素建立维持性血液透析患者久坐行为发生的列线图模型.受试者工作曲线下面积为0.743(95%CI:0.700~0.786),Bootstrap重抽样法进行内部验证后,模型的一致性指数为 0.743.列线图模型拟合度较好(P>0.05);校准曲线图显示,预测概率与实际概率发生率的相关性良好.临床决策曲线图表明模型阈值概率在 0.25~0.91 时,此模型具有较好的临床实用性.结论 基于影响维持性血液透析病人久坐行为的危险因素建立的预测模型具有良好的区分度、一致性与临床实用性,可为预防维持性血液透析病人久坐行为的发生提供指导.
Construction of a nomogram model for the risk of sedentary behavior in maintenance hemodialysis patients
Objective To analyze the influencing factors of sedentary behavior in maintenance hemodialysis patients and to es-tablish a nomogram model for the risk of sedentary behavior.Methods Convenience sampling was used to select 579 patients receiving maintenance hemodialysis at a blood purification center of a tertiary hospital in Wuhu City from January 2024 to June 2024.A general information questionnaire,the international physical activity questionnaire and a single-item questionnaire for fear of falling were used for the survey.Results The incidence of sedentary behavior among the 579 patients was 68.0%(394/579),with an average daily sed-entary time of 378.57 minutes(interquartile range:341.43 to 428.57 minutes).Logistic regression analysis showed that age,total thyroid hormone levels,fear of falling,intradialytic hypotension and nutritional risk index were the influencing factors for sedentary behavior in maintenance hemodialysis patients,and the differences were statistically significant(all P<0.05).A nomogram model for sedentary be-havior in maintenance hemodialysis patients was established based on these 5 independent risk factors.The area under the receiver oper-ating characteristic curve was 0.743(95%CI:0.700~0.786)and the model's consistency index,after internal validation using boot-strap resampling was 0.743.The model had a good fit(P>0.05).The calibration curve shows a strong correlation between the predicted probability and the actual probability of occurrence.The clinical decision curve shows that the model has good clinical practicality when the threshold probability ranged from 0.25~0.91.Conclusion The predictive model based on risk factors affecting sedentary behavior in maintenance hemodialysis patients has good discrimination,consistency and clinical practicality,offering provide guidance for preven-ting sedentary behavior in maintenance hemodialysis patients.

Maintenance hemodialysisSedentary behaviornomogram

张祥、汪秦、王雪燕、陶明芬

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皖南医学院研究生学院,安徽 芜湖 241000

皖南医学院第一附属医院护理部,安徽 芜湖 241000

维持性血液透析 久坐行为 列线图

2025

牡丹江医学院学报
牡丹江医学院

牡丹江医学院学报

影响因子:0.615
ISSN:1001-7550
年,卷(期):2025.46(1)