模式识别与人工智能2024,Vol.37Issue(7) :613-625.DOI:10.16451/j.cnki.issn1003-6059.202407004

基于多模态模糊特征融合的脑龄协同预测算法

Collaborative Brain Age Prediction Algorithm Based on Multimodal Fuzzy Feature Fusion

王静 丁卫平 尹涛 鞠恒荣 黄嘉爽
模式识别与人工智能2024,Vol.37Issue(7) :613-625.DOI:10.16451/j.cnki.issn1003-6059.202407004

基于多模态模糊特征融合的脑龄协同预测算法

Collaborative Brain Age Prediction Algorithm Based on Multimodal Fuzzy Feature Fusion

王静 1丁卫平 1尹涛 1鞠恒荣 1黄嘉爽1
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作者信息

  • 1. 南通大学人工智能与计算机学院 南通 226019
  • 折叠

摘要

深度神经网络可通过训练从大脑图像中预测年龄,作为识别衰老相关疾病的生物标志物.传统的脑龄预测方法往往依赖于单一模态的图像数据,而多模态数据可提供更全面的信息,提高预测精度.然而,现有的多模态融合方法往往不能充分利用不同模态之间的相关性和互补性.为了克服上述问题,文中提出基于多模态模糊特征融合的脑龄协同预测算法(CMFF),设计模糊融合模块和多模态协同卷积模块,可有效利用多模态信息之间的相关信息和互补信息.首先,利用卷积神经网络从多模态脑图中提取特征张量,径向拼接后整合到一个全局特征张量中.然后,利用模糊融合模块学习被模糊化的特征,再将特征应用到多模态协同卷积模块,通过特定的卷积层增强模态间的互补信息.最后,基于性别信息和经过模糊协同处理的特征执行年龄预测回归任务,得到准确的预测年龄.在SRPBS多重障碍MRI数据集上的实验表明,CMFF性能较优.

Abstract

Deep neural networks can be trained to predict age from brain image and the predicted brain age serves as a biomarker for identifying diseases associated with aging.Traditional brain age prediction methods tend to rely on unimodal image data,whereas multimodal data can provide more comprehensive information and improve prediction accuracy.However,existing multimodal fusion methods often fail to fully exploit the correlations and complementarities between different modalities.To overcome these challenges,a collaborative brain age prediction algorithm based on multimodal fuzzy feature fusion(CMFF)is proposed.Fuzzy fusion module and multimodal collaborative convolution module are designed to effectively utilize the correlation and complementary information between the multimodal information.Firstly,feature tensors are extracted from multimodal brain images by a convolutional neural network,and are integrated into a global feature tensor via radial joins.Then,the fuzzy fusion module is employed to learn the fuzzified features,and these features are applied to the multimodal collaborative convolutional module to enhance the complementary information of these features through modality-specific convolutional layers.Finally,the age prediction regression task is performed based on the gender information and the fuzzy collaborative processed features to obtain an accurate predicted age.Experimental results on SRPBS multi-disorder MRI dataset demonstrate the superior performance of CMFF.

关键词

模糊融合/协同卷积/脑龄预测/多模态医学影像/深度学习

Key words

Fuzzy Fusion/Collaborative Convolution/Brain Age Prediction/Multimodal Medical Image/Deep Learning

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基金项目

国家自然科学基金项目(61976120)

国家自然科学基金项目(62006128)

国家自然科学基金项目(62102199)

江苏省自然科学基金项目(BK20231337)

江苏省双创博士计划项目(JSSCBS20230348)

江苏省高等学校自然科学研究重大项目(21KJA510004)

江苏省高等学校自然科学研究面上项目(23KJB520031)

南通市科技局基础科学研究项目(JC2021122)

中国博士后科学基金项目(2022M711716)

出版年

2024
模式识别与人工智能
中国自动化学会,国家智能计算机研究开发中心,中国科学院合肥智能机械研究所

模式识别与人工智能

CSTPCDCSCD北大核心
影响因子:0.954
ISSN:1003-6059
参考文献量1
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