摘要
目的 分析急性脑梗死患者脑微出血的独立危险因素.方法 回顾性分析2018年10月—2020年9月福建省泉州市中医院收治的180例急性脑梗死患者的临床资料,根据患者是否发生脑微出血分为脑微出血患者(61例)和无脑微出血患者(119例).结果 脑微出血患者年龄≥65岁、收缩压升高、舒张压升高及合并糖尿病、心房颤动、高脂血症、冠心病、腔隙性脑梗死、脑白质疏松症、高同型半胱氨酸血症患者占比高于无脑微出血患者,差异有统计学意义(χ2值分别为5.08、29.89、28.47、24.10、9.35、11.27、4.98、7.04、13.27、17.39,P<0.05).多因素logistic回归分析结果显示,合并腔隙性脑梗死、糖尿病、心房颤动、高同型半胱氨酸血症、高脂血症、脑白质疏松症、冠心病及年龄≥65岁、收缩压升高、舒张压升高均为急性脑梗死患者脑微出血发生的独立危险因素,差异有统计学意义(OR值分别为1.76、2.11、2.95、2.37、2.21、2.09、2.37、2.02、2.95、2.68,P<0.05).结论 急性脑梗死患者脑微出血的独立危险因素较多,临床可根据其危险因素对患者进行针对性干预,以降低急性脑梗死患者脑微出血发生的风险,改善患者预后.
Abstract
Objective To analyze the clinical characteristics and related influencing factors of cerebral micro-hemorrhage in patients with acute cerebral infarction.Methods Clinical data for 180 patients with acute ce-rebral infarction admitted to Quanzhou Hospital of Traditional Chinese Medicine between October 2018 and September 2020 were retrospectively collected.The cohort was divided into groups of patients with(61 cases)and without(119 cases)cerebral microbleeds.Results The proportion of≥65 years,increased systolic blood pressure,increased diastolic blood pressure,diabetes mellitus,atrial fibrillation,hyperlipidemia,coro-nary heart disease,lacunar cerebral infarction,white matter osteoporosis,and hyperhomocysteinemia in pa-tients with cerebral microbleeds was higher than in the group without microbleeds.The differences between the two groups were statistically significant(χ2 values were 5.08,29.89,28.47,24.10,9.35,11.27,4.98,7.04,13.27,17.39,respectively;P<0.05).Multivariatelogisticregression analysis showed that age of≥65 years,increased systolic blood pressure,increased diastolic blood pressure,diabetes mellitus,atrial fibrillation,hyperlipidemia,coronary heart disease,lacunar cerebral infarction,white matter osteoporosis,and hyperhomocys-teine were independent risk factors for cerebral microhemorrhage in patients with acute cerebral infarction(OR values were 2.02,2.95,2.68,2.11,2.95,2.21,2.37,1.76,2.09,2.37,respectively;P<0.05).Conclusions There are many independent risk factors for cerebral microbleeds in patients with acute cerebral infarction.Clinical intervention can be carried out according to these risk factors to reduce the risk of cerebral micro-bleeds in patients with acute cerebral infarction and improve patient prognosis.
维普
万方数据