摘要
目的 分析睡眠打鼾与西藏中老年人群骨质疏松之间的关系.方法 对西南区域自然人群队列研究西藏项目点基线数据进行分析,于2018年5月至2019年8月,采用统一设计的电子化问卷对调查对象进行面对面询问调查,收集研究对象的一般资料(性别、年龄、婚姻状况、受教育程度、职业、家庭收入等)、行为生活方式(吸烟、饮酒、睡眠、体力活动等)、健康状况(焦虑、抑郁、自评健康、慢性病患病情况等)和社会支持等.采用logistic回归模型分析睡眠打鼾对骨质疏松患病的影响.结果 共纳入3 483名45～79岁中老年人群,平均年龄(55.81±7.72)岁.睡眠时经常打鼾和偶尔打鼾的比例分别为15.22%和21.99%.调整潜在混在因素后,与从不打鼾者比较,经常打鼾者骨质疏松患病的OR值(95%CI)为1.74(1.30～2.32).亚组分析显示,经常打鼾可增加男性中老年人群骨质疏松的患病风险(OR=1.85,95%CI1.27～2.70);经常打鼾与骨质疏松的关联在中年和老年人群中均有统计学意义,且在老年人群中效应更强(OR=1.85,95%CI1.12～3.03).结论 睡眠打鼾与骨质疏松患病风险相关,男性和老年人群应及早改善睡眠打鼾行为.
Abstract
Objective To analyze the association between snoring and osteoporosis among middle-aged and elderly people in Tibet.Methods Baseline data from the China Multi-Ethnic Cohort(CMEC)study that were collected at the Tibet project site were analyzed.The respondents were interviewed face-to-face with a uni-formly designed electronic questionnaire from May 2018 to August 2019 to collect general information(gender,age,marital status,education level,occupation,and family income),behavior and lifestyle(smoking,alcohol consumption,sleep habits,and physical activity),health status(anxiety,depression,self-rated health,and chronic disease prevalence),and social support.A logistic regression model was used to ana-lyze the effect of snoring during sleep on osteoporosis.Results A total of 3 483 middle-aged and elderly people(age range,45-79 years)were included in the study.The average age of people was(55.81±7.72)years old.The proportions of participants who snored frequently and snored sometimes were 15.22% and 21.99%,respectively.After adjusting for potential confounding factors,the OR(95% CI)of frequent snorers was 1.74(1.30-2.32)compared to those who never snored.Subgroup analysis showed that frequent snoring increased the risk of osteoporosis in middle-aged and elderly men(OR=1.85,95% CI 1.27-2.70).The as-sociation between frequent snoring and osteoporosis was statistically significant in middle-aged and elderly people,and the effect was stronger in elderly people(OR=1.85,95% CI 1.12-3.03).Conclusions Snoring is associated with the risk of osteoporosis.Men and the elderly should treat and improve snoring.
维普
万方数据