Efficacy and safety of a 3D-slicer combined with neuroendoscopy in the treatment of hypertensive basal intracerebral hemorrhage
郭伟 1刘颉 1肖哲 1李争民1
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作者信息
1. 庆阳市人民医院神经外科,甘肃 745000
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摘要
目的 探讨3D-slicer联合内镜手术治疗高血压基底核脑出血的临床效果.方法 选取2018年4月至2022年5月庆阳市人民医院收治的116例高血压基底核脑出血患者作为研究对象,按照治疗方案不同分为研究组和对照组,每组58例.研究组采用3D-slicer技术联合神经内镜清除术治疗,对照组采用CT定位组钻孔引流术治疗,比较两组手术参数指标、血肿消除情况、颅内压水平、格拉斯哥昏迷评分法(Glasgow coma scale,GCS)评分、术后基本情况及术后6个月预后情况.结果 研究组手术时间长于对照组,术中失血量低于对照组,差异有统计学意义(P<0.05).术后1、7 d,研究组血肿清除率均高于对照组,差异有统计学意义(P<0.05).术前,两组GCS评分和颅内压水平比较,差异无统计学意义(P>0.05);术后7d,研究组GCS评分高于对照组,颅内压水平低于对照组,差异有统计学意义(P<0.05).研究组引流管拔除时间、术后7 d水肿带直径及术后颅内感染发生率低于对照组,差异有统计学意义(P<0.05).随访6个月后,研究组残疾率和死亡率低于对照组,差异有统计学意义(P<0.05).结论 3D-slicer联合神经内镜术治疗高血压基底核脑出血效果及安全性良好.
Abstract
Objective To determine the clinical efficacy of a 3D-slicer combined with endoscopic surgery in the treatment of hypertensive basal nucleus hemorrhage.Methods One hundred sixteen patients with hyperten-sive basal ganglia intracerebral hemorrhage admitted to the Qingyang People's Hospital from April 2018 to May 2022 were selected as study subjects and divided into experimental and control groups according to the treatment scheme,with 58 patients in each group.The experimental group was treated with 3D-slicer tech-nology combined with neuroendoscopic clearance surgery,while the control group was treated with CT local-ization drilling drainage surgery.The surgical parameters,hematoma elimination,intracranial pressure level,Glasgow coma scale(GCS)score,postoperative basic data,and 6-month prognosis were compared between the two groups.Results The surgical time for the experimental group was longer than the control group,while the blood loss was less than the control group(P<0.05).The hematoma clearance rate in the exper-imental group was higher than the control group on the 1st and 7th day postoperatively(P<0.05).There were no statistically significant differences in preoperative GCS scores and intracranial pressure levels between the two groups(P>0.05).The GCS scores of patients in the experimental group were higher than the con-trol group on the 7th day postoperatively,and the intracranial pressure levels were lower than the control group(P<0.05).The time of drainage tube removal,the diameter of the edema zone 7 days postoperatively,and the rate of intracranial infection and rebleeding in the experimental group were lower than the control group(P<0.05).After 6 months of follow-up evaluations,the mortality rate of patients in the experimental group was lower than in the control group,and the difference was statistically significant(P<0.05).Conclusions The efficacy and safety of a 3D-slicer combined with neuroendoscope in the treatment of hypertensive basal nucleus intracerebral hemorrhage are good.
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