Liver cancer is a malignant tumor with a high mortality rate.With the continuous development of targeted drugs,immunotherapy and other technological means,translational therapy has become a consensus in the treatment of advanced liver cancer.The liver's inherent immune tolerance,tumor tissue,and various immune components constitute a dynamically changing liver cancer microenvironment.The immune escape in the microenvironment of liver cancer is the main obstacle to current immunotherapy.Cellular immunity is an important component of anti-tumor immunity,and the status and function of immune cells are closely related to cancer prognosis.This article reviews the progress of tumor infiltrating lymphocytes in the tumor microenvironment of hepatocellular carcinoma,in order to benefit the exploring of targeted antitumor therapy.
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