SMILE与FS-LASIK术后角膜上皮重塑的临床研究

扫码查看

原文链接

万方数据
维普

中文摘要：目的:比较飞秒激光小切口角膜基质透镜取出术(SMILE)与飞秒激光辅助准分子激光原位角膜磨镶术(FS-LASIK)术后角膜上皮厚度(CET)的变化特点.方法:收集2022-12/2023-11在乌鲁木齐爱尔眼科医院接受屈光手术患者187例187眼.按手术方式分为SMILE组110例110眼和FS-LASIK组77例77眼.应用眼前节光学相干断层扫描技术(OCT)分别于术前和术后1 wk,1、3、6 mo测量患者的CET.结果:比较术后6 mo时角膜中央区、旁中央区、中周区角膜上皮厚度变化量(△CET),SMILE的特点为中央区增厚最明显,中周区上皮最少;FS-LASIK的特点为旁中央区增厚最明显,中周区最少.术后1 wk,1、3、6mo时SMILE与FS-LASIK组角膜0-7 mm范围的平均△CET与术前等效球镜均具有相关性.结论:SMILE和FS-LASIK术后6 mo内上皮增厚程度随时间变化有相似的趋势和不同的特点,二者△ CET均与术前等效球镜正相关.

外文标题：Clinical research on corneal epithelium remodeling after small incision lenticule extraction and femtosecond laser-assisted in situ keratomileusis

外文摘要：·AIM:To compare the changes in corneal epithelial thickness(CET)after small incision lenticule extraction(SMILE)and femtosecond laser-assisted in situ keratomileusis(FS-LASIK).·METHODS:A total of 187 patients(187 eyes)who underwent either SMILE or FS-LASIK at Urumqi Aier Eye Hospital between December 2022 and November 2023 were collected.The patients were divided into SMILE group and FS-LASIK group according to surgical methods.The CET of the patients was measured by optical coherence tomography(OCT)system before surgery and at 1 wk,1,3,and 6 mo postoperatively.·RESULTS:Changes in corneal epithelial thickness(△CET)in the central,paracentral,and mid-peripheral regions were compared at 6 mo postoperatively.The SMILE group was characterized by the most significant thickening in the central area and the least thickening in the mid-peripheral area;while the FS-LASIK group was characterized by the most significant thickening in the paracentral area and the least thickening in the mid-peripheral region.At 1 wk,1,3,and 6 mo postoperatively,within the 0-7 mm corneal area,the△CET for both the SMILE and FS-LASIK groups was correlated with the preoperative spherical equivalent.·CONCLUSION:Within 6 mo postoperatively,both SMILE and FS-LASIK showed a similar trend in epithelial thickening but with distinct characteristics.The change in corneal epithelial thickness for both procedures was positively correlated with the preoperative diopter.

外文关键词：

small incision lenticule extraction(SMILE)femtosecond laser-assisted in situ keratomileusis(FS-LASIK)corneal epithelium remodelingoptical coherence tomography(OCT)

作者：

张杨婧、马立威、张帆、柯春梅、王瑞夫、祖丽皮娅

展开 >

作者单位：

(230031)中国安徽省合肥市,安徽医科大学爱尔眼科医学中心

(830000)中国新疆维吾尔自治区乌鲁木齐市,乌鲁木齐爱尔眼科医院

(110000)中国辽宁省沈阳市,沈阳爱尔卓越眼科医院

关键词：

飞秒激光小切口角膜基质透镜取出术(SMILE) 飞秒激光辅助准分子激光原位角膜磨镶术(FS-LASIK) 角膜上皮重塑光学相干断层扫描技术(OCT)

出版年：

2025

DOI：