Current status and prospect of the correlation between retinal vascular characteristics and coronary heart disease
Coronary atherosclerotic heart disease(CAD)is a cardiovascular disease with high morbidity and mortality.Early and accurate prediction is clinically important to prevent the disease progression and reduce the mortality rate.As the only microvessel that can be directly and non-invasively observed in the human body,the retinal vasculature has similar anatomical structure and physiological characteristics with coronary artery.Atherosclerosis occurs under the influence of common genetic phenotypes and environmental influences,which provides a potential co-morbidity study between the retinal vasculature and the coronary artery diseases.As a good window to observe the retinal vasculature,predicting CAD by using fundus vascular features has been the focus of research.The in-depth integration of fundus imaging and artificial intelligence can provide objective quantitative retinal vascular characteristics for the assessment of CAD,which is of great clinical value.We comprehensively reviewed the current status of research on the correlation between retinal vascular characteristics and CAD,and analyze the latest challenges and prospects in this research area.
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