This study proposes a coagulation-dissolved air flotation and microwave drying processes based on biologic coagulant for harvesting cyanobacteria biomass,and a pilot system with a treatment capacity of 20 m3/h was developed.Continuous operation in Lake Tai demonstrated that the system achieved a harvesting efficiency of up to 95%for cyanobacterial biomass,with the moisture content of the biomass reduced to below 85%after dehydration.After 10 min of continuous microwave drying,the moisture content of the biomass was further reduced to below 10%,with no adverse effects on the main nutrients,such as proteins and sugars.Further techno-economic and cost sensitivity analyses revealed that the total cost of harvesting and drying cyanobacterial biomass was 4 134.1 ¥/t dry biomass,with bioflocculant costs accounting for more than 50%of this total.The processing costs were found to be significantly influenced by the dosage and cost of bioflocculants,as well as the hourly microwave drying capacity.