To study the differences on antioxidant activity and chemical ingredients and evaluate the quality of Lycium barb arum from different regions.DPPH method and hydroxyl radical scavenging methods were used to evaluate the antioxidant activity of Lycium barb arum.The content of polysaccharides,flavonoids,and polyphenols were mesured by colorimetric method.And the similarity of Lycium barbarum from different regions was analyze by cluster method.Lycium barbarum from Gansu showed the strongest scavenging effect on DPPH and hydroxyl radical with IC50 of 0.462 mg/mL and 2.259 mg/mL respectively.The content of crude polysaccharide,flavonoids and water-soluble extract of Lycium barb arum from Jilin region,and polyphenols of Lycium barb arum from Gansu region were the highest.Correlation analysis showed that polyphenols and flavonoids were the main ingredients of Lycium barb arum that inhibited hydroxyl radicals.The chemical ingredients and antioxidant activity of Lycium barbarum were differences from different regions,but the overall quality has certain similarities.
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