摘要
黑芝麻富含芝麻素、松脂素等活性成分,具有滋养脾肺、补肝益肾、养发黑发的功能.毛发颜色与毛囊内黑素细胞酪氨酸酶激活促进黑色素的生成水平密切相关.以人体黑素细胞结构较相似的小鼠黑色素瘤细胞B16为对象,研究黑芝麻中芝麻素、松脂素及黑芝麻产品对B16细胞内酪氨酸酶活性和黑色素生成的影响.结果表明,芝麻素和松脂素可提高B16细胞内酪氨酸酶的活性,促进黑色素生成.核桃芝麻黑豆粉和黑芝麻丸产品醇和水提取物也具有促进B16细胞内酪氨酸酶活性和黑色素生成的作用.因此,芝麻素和松脂素及黑芝麻产品能有效促进黑色素生成,可能具有乌发潜力.
Abstract
Black sesame is abundant in sesamin and pinoresinol,possessing the capacity to nourish the spleen,lung,liver,kidney,and hair.The pigmentation of hair is intricately linked to the activity of tyrosinase,an enzyme that stimulates melanin production in the melanocytes of hair follicles.The study investigated the impact of sesamin,pinoresinol and black sesame products on tyrosinase activity and melanin production in B16 cells,a type of mouse melanoma cells similar to human melanocyte structure.The findings revealed that sesamin and pinoresinol,exhibited the ability to enhance tyrosinase activity in B16 cells and stimulate melanin production.The ethanol and water extract of walnut sesame black bean powder and black sesame pill could also promote the production of melanin in B16 cells.Hence,it could be inferred that sesamin,pinoresinol,and black sesame products possess the capability to stimulate melanin synthesis,thereby exhibiting the potential to induce hair pigmentation.
万方数据