Glucose optimization-based early intermittent enteral nutrition in patients with combined stress hyperglycemia after heart valve replacement
Objective To explore the application effect of early intermittent enteral nutrition program based on glucose optimization in patients with combined stress hyperglycemia after heart valve replacement.Methods An early intermittent enteral nutrition program after glucose optimization was constructed for patients with combined stress hyperglycemia after heart valve replacement.Totally 158 patients with combined stress hyperglycemia after heart valve replacement in cardiothoracic surgery intensive care unit(CICU)in a tertiary grade-A hospital in Shanghai between May 2022 and May 2023 were divided into control group(n=78)and observation group(n=80)by using random number table method.The control group received conventional enteral nutrition and glucose management program,and the observation group the early intermittent enteral nutrition program based on glucose optimization.Quality indicators of blood glucose management and nutrition-related outcome indicators of the two groups were compared.ResuIts After the implementation of early intermittent enteral nutrition program based on glucose optimization,the maximum blood glucose fluctuation amplitude,insulin use time,and the incidence of hypoglycemia of the observation group were significantly lower or shorter than those of the control group(P＜0.05);glucose goal range time was significantly longer than that of the control group,and the difference was statistically significant(P＜0.05);nutrition-related indicators(serum pre-serum protein,hemoglobin,7d calorie attainment rate)of patients in the observation group were higher than those in the control group,showing statistical significance(P＜0.05).Conclusion Early intermittent enteral nutrition program based on glucose optimization can effectively improve the nutritional status of patients with combined stress hyperglycemia after heart valve replacement,reduce blood glucose fluctuation,and improve the quality of blood glucose management,which is of certain scientific and practical significance.
early enteral nutritionblood glucose managementintermittent feedingpost-heart valve replacementstress-induced hyperglycemia
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