摘要
目的 评价125I放射性粒子植入治疗腹腔转移癌的可行性、疗效及治疗优势.方法 回顾分析放射性粒子植入治疗的8例腹腔转移癌患者的临床资料.结果 3例盆腔转移者中2例Ⅱ级疼痛患者术后疼痛缓解,1例Ⅲ级疼痛患者术后1周疼痛逐渐降至Ⅰ级.1例患侧下肢水肿患者术后1月水肿完全消失.1例输尿管受压患者经输尿管支架植入后腰背部疼痛消失.3例会阴坠胀感患者至术后2月复查坠胀感消失.2例腹壁转移患者术后1天疼痛消失,转移病灶逐渐减小.胰周及腹膜后多发淋巴结转移病例术后复查肿大淋巴结消失.结论 放射性粒子植入治疗腹腔转移癌可有效提高患者的生活质量.
Abstract
Objective To assess the feasibility,efficacy,and therapeutic advantages of radioactive 125I seed implantation for the treatment of abdominal metastases.Methods The clinical data of eight patients with ab-dominal metastases treated with radioactive 125I seed implantation were retrospectively analyzed.Results Of the three pelvic metastasis cases,two patients with grade Ⅱ pain had postoperative pain relief,and one patient with grade Ⅲ pain had a gradual decrease in pain to grade Ⅰ one week after surgery.One patient with lower extremity edema had complete disappearance of edema one month after surgery.The lumbar back pain disappeared after ure-teral stent implantation in one patient with ureteral compression.In three patients with perineal drop sensation,the discomfort disappeared at the 2-month postoperative follow-up.In two patients with abdominal wall metastases,the pain disappeared one day after surgery,and the metastatic lesions gradually decreased in size.Postoperative re-evaluation of patients with multiple peripancreatic and retroperitoneal lymph node metastases showed the disap-pearance of lymph node enlargement.Conclusion Radioactive 125I seed implantation can effectively improve the life quality of patients with abdominal metastases.
基金项目
吴阶平医学基金会项目(Zkjc60121221701151721)
NETL
NSTL
万方数据