首页|关注甲状腺癌术后低钙血症的防治

关注甲状腺癌术后低钙血症的防治

Strengthening the prevention and treatment of postoperative hypocalcemia of thyroid cancer patients

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手术治疗是各型甲状腺癌的重要治疗方法,手术可引起单个或多个甲状旁腺损伤或血液供给障碍,致术后甲状旁腺素明显下降和低钙血症.长期低钙血症,可造成患者生理和心理上的巨大痛苦.部分患者甲状旁腺虽能代偿,但长期负钙平衡、术后低血钙刺激其余甲状旁腺增生、肿大,导致甲状旁腺功能增强/亢进,引起骨质疏松、泌尿系统结石、转移性血管钙化、全身钙质异常迁徙沉着等并发症.故加强对甲状腺癌术后低钙血症病因、危害认识,早评估早发现,积极在甲状腺癌术前、术中、术后及长期随访各个环节进行干预,可有效降低低钙血症的发生和严重程度,提高患者生活质量和改善预后.
Surgery is the important treatment for each type of thyroid cancer.Single or multiple parathy-roid injuries or blood supply disorders may occur during the operation,resulting in dramatic decline of parathyroid hormone and hypocalcemia after operation,which is common in clinical practice.After discharge,chronic hypocal-cemia can cause great physical and psychological pain to patients.Although the residual parathyroid glands can compensate after surgery in some cases,long-term negative calcium balance and postoperative hypocalcemia may cause excessive hyperplasia of the residual parathyroid glands,resulting in parathyroid hyperfunction or even hy-perparathyroidism,which can lead to osteoporosis,urinary calculi,metastatic vascular calcification,and systemic abnormal migratory calcium deposits.It's advisable to enhance the awareness of the cause and harm of the postop-erative hypocalcemia,evaluate and diagnose it early,and actively intervene in every stage of before,during and af-ter the operation and long-term follow-up,which can effectively reduce the occurrence and severity of hypocalcemia and improve the postoperative life quality and the prognosis.

Thyroid cancerHypocalcemiaHypoparathyroidismHyperparathyroidism

程小春、孔令泉、母力元、涂江渝、王元元、吴凯南

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重庆医科大学附属第一医院乳腺甲状腺外科,重庆 400016

甲状腺癌 低钙血症 甲状旁腺功能减退 甲状旁腺功能亢进

2024

中华内分泌外科杂志
中华医学会

中华内分泌外科杂志

CSTPCD
影响因子:0.657
ISSN:1674-6090
年,卷(期):2024.18(4)