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一种普外科用亲水型中药聚氨酯敷料制备及应用

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为提高普外科用聚氨酯泡沫的性能,对聚氨酯泡沫敷料进行制备优化,并探究其临床应用效果.实验结果表明,当用水量为60 pbw,稳泡剂硅油L580用量为7.5 pbw,PEG分子量为4 000,交联剂甘油的用量为0.75时,得到的聚氨酯泡沫敷料的性能最佳;将该敷料临床用于普外科胃肠道手术患者,使用实验制备的聚氨酯泡沫敷料的患者伤口愈合率要明显高于传统的水凝胶结合无菌纱布组患者(P<0.05).由此得出,研究制备的聚氨酯泡沫材料可用于普外科患者临床护理,具有一定的临床应用价值.
Preparation and application of hydrophilic traditional Chinese medicine polyurethane dressing for general surgery
In order to improve the performance of polyurethane foam for general surgery,the preparation of polyure-thane foam dressing was optimized,and its clinical application effect was explored.The results showed that the poly-urethane foam dressing had the best performance when the water consumption was 60 pbw,the content of silicone oil L580 was 7.5 pbw,the molecular weight of PEG was 4 000,and the content of cross-linking agent glycerin was 0.75.When the dressing was used for gastrointestinal surgery patients in general surgery,the wound healing rate of the polyurethane foam dressing prepared in this experiment was significantly higher than that of the traditional hy-drogel combined with sterile gauze group(P<0.05).Therefore,the polyurethane foam material prepared in this study can be used for the clinical care of patients in general surgery,and has certain clinical application value.

polyurethane materialcross-linking agent glycerolabsorption ratefoam dressingclinical nursing

韩磊、颜海华、梅广红、焦黛妍

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江苏省海安市人民医院,江苏 海安 226600

南京中医药大学,江苏 南京 210000

聚氨酯材料 交联剂甘油 吸收率 泡沫敷料 临床护理

2025

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湖北省襄樊市胶粘技术研究所

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影响因子:0.364
ISSN:1001-5922
年,卷(期):2025.52(1)