Correlation analysis of left ventricular global myocardial work and left ventricular remodeling after emergency PCI in patients with ST-segment elevation myocardial infarction
Objective:To explore the correlation analysis of left ventricular global myocardial work(LVGMW)and left ventricular remodeling(LVR)after emergency percutaneous coronary intervention(PCI)in patients with acute ST-segment elevation myocardial infarction(STEMI).Methods:From January 2019 to December 2020,54 consec-utive patients(45 males)who underwent emergency PCI for AMI were included with an average age of(59.7±12.4)years old.Comprehensive echocardiography was performed for patients who underwent emergency PCI for STEMI 48 hours(48 h)and 6 months after PCI.Left ventricular ejection fraction(LVEF),left ventricular end-di-astolic volume(LVEDV),left ventricular global longitudinal strain(LVGLS)and left ventricular global work indices(LVGWI)were assessed.Left ventricle(LV)remodeling(LVR)was defined as an increase of 15%of LVEDV from 48 hours to 6 months after surgery.Multivariate Logistic regression analysis was used to evaluate the correlation of LVGMW and LVR.Results:Left ventricular remodeling occurred in 17 patients at 6 months after surgery.48 h left ventricular global work index(LVGWI)in the LVR group was significantly lower than that in non-LVR group[(1 099.7±426.1)mmHg%vs.(1 582.3±557.6)mmHg%,P =0.003].Multivariate Logistic regression anal-ysis showed that LVGWI within 48 h was an independent risk factor for LVR after emergency PCI in STEMI pa-tients,the area under ROC curve was 0.757(95%CI 0.622-0.891,cut-off point 1 382 mmHg%,specificity 64.9%,sensitivity 82.4%,P =0.035).Conclusion:Lower48 h LVGWI was an independent risk factor for LVR in STEMI patients undergoing emergency PCI.
left ventricular global myocardial workleft ventricular global work indexST-segment elevation my-ocardial infarctionpercutaneous coronary interventionleft ventricular remodeling
NETL
NSTL
万方数据
维普
