The value of blood sCD14-ST and procalcitonin differentiating different types of pathogenic bacteria in septic children
Objective:To explore the diagnostic value of soluble leukocyte differentiation antigen 14 subtype(sCD14-ST)and procalcitonin(PCT)in children with sepsis with different types of pathogen infction.Methods:A total of 98 children with sepsis(sepsis group)admitted to the Children's Hospital of Nanjing Medical University from January 2019 to May 2021 were collected.All cases were conformed to the diagnostic criteria of sepsis 3.0.Ac-cording to the results of blood culture,those children were divided into Gram-positive cocci group(G+group),Gram-negative bacilli group(G-group)and blood culture negative group.Meanwhile,90 healthy children were se-lected as the control group.Results:Compared with the control group,sCD14-ST and PCT were highly expressed in children with sepsis(P＜0.05).The levels of serum sCD14-ST and PCT in children with positive blood culture were higher than those in children with negative blood culture(P＜0.05).The predictive value of sCD14-ST for positive blood culture in children with sepsis were higher than that of PCT.Meanwhile,the predictive value of PCT for identificating G-or G+bacteria in children with sepsis was significantly higher than that of sCD14-ST.Conclusion:The value of sCD14-ST in the early prediction of positive blood culture in children with sepsis is high-er than that of PCT,and PCT is valuable for the identification of pathogenic bacteria in children with sepsis.The results show that the combined detection of sCD14-ST and PCT has predictive value in the diagnosis of etiology in children with sepsis.
万方数据
维普
