首页|老年脑梗死鼻饲患者发生吸入性肺炎的危险因素分析及预测模型构建

老年脑梗死鼻饲患者发生吸入性肺炎的危险因素分析及预测模型构建

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目的:探讨脑梗鼻饲患者发生吸入性肺炎的危险因素并构建预测模型.方法:回顾性分析2021年6月至2023年6月期间于本院住院治疗的155例需接受鼻饲治疗的脑梗死老年患者的临床资料,根据住院期间是否出现吸入性肺炎分为吸入性肺炎组(n=71)和非吸入性肺炎组(n=84).比较两组患者临床风险因素,确定老年脑梗死鼻饲患者发生吸入性肺炎的危险因素,根据结果构建预测模型,绘制ROC曲线分析预测模型对吸入性肺炎的预测价值.结果:纳入155例接受鼻饲治疗的脑梗死患者,吸入性肺炎发生率为45.81%(71/155).逐步 Logistic 回归分析显示置管次数 1 次以上(OR=2.380,95%CI1.092~5.452)、自主咳嗽减弱或消失(OR=3.053,95%CI 1.697~8.751)、呕吐(OR=3.182,95%CI1.304~8.186)、日鼻饲量≥1 000 mL(OR=3.318,95%CI 1.155~5.836)、镇静催眠药(OR=3.598,95%CI 1.197~7.421)、无吞咽功能训练(OR=2.062,95%CI 1.128~6.962)、格拉斯哥昏迷(GCS)评分≤ 12 分(OR=4.649,95%CI 1.148~9.970)是老年脑梗死鼻饲患者发生吸入性肺炎的危险因素.根据上述危险因素构建风险预测模型,该模型预测老年脑梗死鼻饲患者发生吸入性肺炎的ROC曲线下面积为0.823(95%CI0.750~0.896),敏感度和特异度分别为0.81和0.75.结论:根据老年脑梗死鼻饲患者发生吸入性肺炎的危险因素构建的风险预测模型对老年脑梗死鼻饲患者护理有较大参考价值,且具有便利、易操作的优点,适合临床应用.
Analysis of risk factors and construction of a predictive model for aspiration pneumonia in elderly nasogastric feeding patients with cerebral infarction
Objective:To analyze the risk factors and construct a prediction model for aspiration pneumonia in elderly patients with cerebral infarction and nasal feeding.Methods:The clinical data of 155 elderly patients with cerebral infarction who needed nasal feeding in our hospital from June 2021 to June 2023 were retrospectively ana-lyzed.According to the presence or absence of aspiration pneumonia during hospitalization,they were divided into aspiration pneumonia group(n=71)and non-aspiration pneumonia group(n=84).The clinical risk factors were compared between the two groups to determine the risk factors of aspiration pneumonia in elderly patients with cere-bral infarction and nasal feeding.The prediction model was constructed according to the results,and the receiver operating characteristic(ROC)curve was drawn to analyze the predictive value of the prediction model for aspiration pneumonia.Results:A total of 155 patients with cerebral infarction who received nasal feeding were included in this study.The incidence of aspiration pneumonia was 45.81%(71/155).Stepwise Logistic regression analysis showed that the number of catheter insertions>1(OR=2.380,95%CI 1.092-5.452),spontaneous cough dimin-ished or disappeared(OR=3.053,95%CI 1.697-8.751),vomiting(OR=3.182,95%CI 1.304-8.186),nasal feeding quantity ≥1 000 mL(OR=3.318,95%CI 1.155-5.836),sedative hypnotics(OR=3.598,95%CI 1.197-7.421),without swallowing function training(OR=2.062,95%CI 1.128-6.962),Glasgow coma scale(GCS)score ≤12(OR=4.649,95%CI 1.148-9.970)were the risk factors of aspiration pneumonia in se-nile cerebral infarction patients with nasal feeding.Risk prediction model was established in accordance with the above risk factors for aspiration pneumonia in elderly patients with cerebral infarction.The area under the ROC curve of the model was 0.823(95%CI 0.750-0.896),and the sensitivity and specificity were 0.81 and 0.75,respectively.Conclusion:The risk prediction model constructed according to the risk factors of aspiration pneumo-nia in elderly cerebral infarction patients with nasal feeding has great reference value for the nursing of elderly cere-bral infarction patients with nasal feeding,and has the advantages of convenience and easy operation,which is suit-able for clinical application.

cerebral infarctionaspiration pneumoniaprediction modelROC curve

徐敏、杨露

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南京市中心医院老年科,江苏南京 210000

脑梗死 吸入性肺炎 预测模型 ROC曲线

2024

东南大学学报(医学版)
东南大学

东南大学学报(医学版)

CSTPCD
影响因子:1.374
ISSN:1671-6264
年,卷(期):2024.43(5)