Predictive value of serum AMH,INHB combined with transvaginal color Doppler ultrasound for pregnancy outcomes on IVF-ET assisted pregnancy patients
Objective:To explore the value of serum anti Mullerian hormone(AMH)and inhibin B(INHB)com-bined with transvaginal ultrasound in predicting pregnancy outcomes in patients undergoing in vitro fertilization and embryo transfer(IVF-ET)assisted pregnancy.Methods:A total of 160 patients who underwent IVF-ET assisted pregnancy in our hospital from January 2019 to January 2023 were regarded as research subjects.They were separa-ted into non pregnant group(n=86)and pregnant group(n=74)based on pregnancy outcomes.The serum AMH,INHB levels,and vaginal ultrasound results of the two groups were compared;ROC curve was applied to analyze the predictive value of serum AMH,INHB combined with transvaginal ultrasound for pregnancy outcomes in IVF-ET assisted patients;Multivariate Logistic regression was used to analyze the influencing factors of pregnancy out-comes in patients undergoing IVF-ET.Results:Compared with the pregnant group,the number of oocytes re-trieved,AMH and INHB levels in the non pregnant group were significantly reduced(P＜0.05).The results of va-ginal ultrasound examination showed that the thickness of endometrium in the non pregnant group was significantly higher than that in the pregnant group(P＜0.05).ROC curve showed that the AUC of AMH,INHB combined with vaginal ultrasound to predict the pregnancy outcome of IVF-ET assisted pregnancy patients was 0.956,with a sensi-tivity of 95.35％and a specificity of 83.78％,which was better than AMH,INHB,and vaginal ultrasound alone(Zcombined detection-AMH=4.543,Zcombined detection-INHB=3.733,Zcombined detection-endometrial thickness=4.511,all P＜0.001).M u l t-ivariate Logistic regression analysis showed that the number of oocytes retrieved,AMH,INHB levels and endometri-al thickness were the influencing factors of pregnancy outcomes in patients with IVF-ET.Conclusion:Serum AMH,INHB combined with transvaginal ultrasound has certain predictive value for IVF-ET assisted pregnancy patients.
anti-Mullerian hormoneinhibin Btransvaginal color Doppler ultrasoundin vitro fertilization and embryo transferassisted pregnancy
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维普
