The analysis of severity and prognosis factors in patients with severe fever with thrombocytopenia syndrome
Objective:To explore the influence of early indicators in patients on the severity and prognosis of se-vere fever with thrombocytopenia syndrome(SFTS).Methods:The clinical data of 183 patients who were diag-nosed as SFTS in Lu'an People's Hospital between 2023 and 2024 were collected.According to the clinical data,the patients were divided into 112 cases in the non-severe group and 71 cases in the severe group.The severe group was further divided into the good prognosis group and the poor prognosis group.Then,the differences in various in-dicators of each group in the early stage were compared and analyzed.Results:The age,Dabie bandavirus(DBV)load,PLT,PT,APTT,RATI,TT,FDP,D-dimer,CK,LDH,AST,IBL,Urea and Cr in the severe group were significantly higher than those in the non-severe group(P＜0.05).The serum levels of Ca2+,Mon and Lym in the severe group were significantly lower than those in the non-severe group(P＜0.05).The age,DBV load,PT,APTT,RATI,TT,FDP,D-dimer,AST and IBL in the poor prognosis group were significantly higher than those in the good prognosis group(P＜0.05),and the proportion of patients with renal insufficiency,respiratory failure or shock in the poor prognosis group was significantly higher than that in the good prognosis group(P＜0.05).Logistic regression analysis showed that the decrease of Lym and the increase of TT and Cr had a statistically significant effect on the exacerbation of SFTS patients(P＜0.05).The increase of IBL had a statistically significant effect on the poor prognosis of severe SFTS patients(P＜0.05).Conclusion:The low Lym level and the high TT,IBL and Cr values in the early stage of SFTS patients have certain reference value for predicting the severity of the disease and poor prognosis.In addition,clinicians may need to be alert to the occurrence of renal insufficiency,respiratory failure and shock when preventing the deterioration of the condition of critically ill patients.
severe fever with thrombocytopenia syndromeDabie bandavirusdisease severityprognosis
万方数据
维普
