Investigation on the epidemiological characteristics of Mycoplasma pneumoniae infection in preschool in Xuzhou city and analysis of the influencing factors for poor outcome
Objective:To investigate the epidemiological characteristics of Mycoplasma pneumoniae(MP)infec-tion in preschool children in Xuzhou city,and analyze the influencing factors of poor outcome.Methods:The clini-cal data of 3 771 preschool children with respiratory infections who received inpatient treatment in our hospital from January 2020 to October 2023 were retrospectively analyzed,and the epidemiological characteristics of MP infected children were screened for analysis.They were divided into poor outcome group and good outcome group according to the outcome of MP infection in children,and the general informations of the two groups were compared.The the influencing factors of poor outcome in preschool children with MP infection were analyzed by using multivariate Lo-gistic regression method.Results:788 cases(accounting for 20.90％)of MP in preschool children with respiratory infections.The infection rate of girls was higher than that of boys(22.20％vs 19.27％).The infection rate in ur-ban areas was higher than that in rural areas(22.86％vs 18.03％).Winter(23.21％)had the highest infection rate in different seasons,and pneumonia(31.62％)had the highest infection rate among different types of diseases.The incidence of poor outcome in preschool children with MP infection was 28.68％(226/788).A total of 217 pairs were matched.After matching,there were no statistically significant differences in gender,age,white blood cell count(WBC),hemoglobin(Hb),albumin(Alb)levels at admission and the use of glucocorticoids between the groups(P＞0.05).The C-reactive protein(CRP)level,proportion of severe cases at admission,proportion of con-current infections with other pathogens,proportion of extrapulmonary complications,and duration of fever were all higher in the poor outcome group than those in the good outcome group(P＜0.05),while the platelet count(PLT)level at admission was lower than that in the good outcome group(P＜0.05).Multivariate Logistic regression analy-sis showed that severe illness at admission,decreased PLT levels at admission,increased CRP levels at admission,concurrent infections with other pathogens,extrapulmonary complications and prolonged fever duration were all risk factors for poor outcomes in preschool children with MP infections(OR values were 4.289,0.715,2.497,2.591,3.071,2.389,P＜0.05).Conclusion:The infection rate of MP in preschool children has been increasing year by year,mainly in girls,urban areas,winter and pneumonia.Severity,duration of fever,PLT level,CRP level,concomitant infections with other pathogens,extrapulmonary complications are all factors influencing poor outcome of preschool children with MP infection.
万方数据
维普
