首页|Extradural contralateral S1 nerve root transfer for spastic lower limb paralysis

Extradural contralateral S1 nerve root transfer for spastic lower limb paralysis

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The current study aims to ascertain the anatomical feasibility of transferring the contralateral S1 ventral root(VR)to the ipsilateral L5 VR for treating unilateral spastic lower limb paralysis.Six formalin-fixed(three males and three females)cadavers were used.The VR of the contralateral S1 was transferred to the VR of the ipsilateral L5.The sural nerve was selected as a bridge between the donor and recipient nerve.The number of axons,the cross-sectional areas and the pertinent distances between the donor and recipient nerves were measured.The extradural S1 VR and L5 VR could be separated based on anatomical markers of the dorsal root ganglion.The gross distance between the S1 nerve root and L5 nerve root was 31.31(±3.23)mm in the six cadavers,while that on the diffusion tensor imaging was 47.51(±3.23)mm in 60 patients without spinal diseases,and both distances were seperately greater than that between the outlet of S1 from the spinal cord and the ganglion.The numbers of axons in the S1 VRs and L5 VRs were 13 414.20(±2 890.30)and 10 613.20(±2 135.58),respectively.The cross-sectional areas of the S1 VR and L5 VR were 1.68(±0.26)mm2 and 1.08(±0.26)mm2,respectively.1n conclusion,transfer of the contralateral S1 VR to the ipsilateral L5 VR may be an anatomically feasible treatment option for unilateral spastic lower limb paralysis.

paralysisspinal nerve rootsnerve transferankle joint

Jiang Cao、Jie Chang、Chaoqin Wu、Sheng Zhang、Binyu Wang、Kaixiang Yang、Xiaojian Cao、Tao Sui

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Department of Orthopedics,the First Affiliated Hospital of Nanjing Medical University,Nanjing,Jiangsu 210029,China

Department of Orthopedics,the Second Affiliated Hospital of Nanjing Medical University,Nanjing,Jiangsu 210029,China

National Natural Science Foundation of China

81871773

2023

生物医学研究杂志(英文版)
南京医科大学

生物医学研究杂志(英文版)

CSCD
影响因子:0.794
ISSN:1674-8301
年,卷(期):2023.37(5)
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