Venous thromboembolism(VTE)is the third most common cardiovascular disease worldwide,and its incidence continues to rise.Coagulation factor ⅩⅢ(F ⅩⅢ,factor ⅩⅢ),also known as fibrin stabilization factor,is involved in multiple stages of the clotting cascade.Recent studies have found that F ⅩⅢ is a key factor in determining the volume,structure and stability of venous thrombosis,and may play an important role in the formation,shedding or dissolution of deep venous thrombosis.This paper reviews the research progress of F ⅩⅢ and VTE,in order to provide new ideas for the prevention,diagnosis and treatment of VTE.
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