卡前列素氨丁三醇及麦角新碱联合一次性宫腔球囊预防高危产妇产后出血的临床效果
Clinical Effect of Combination of Carboprost Tromethamine,Ergometrine and Disposable Intrauterine Balloon in the Prevention of Postpartum Hemorrhage in High-Risk Pregnant
易瑾1
作者信息
- 1. 贵州航天医院产科,贵州遵义,563000
- 折叠
摘要
目的:探讨卡前列素氨丁三醇及麦角新碱联合一次性宫腔球囊预防高危产妇产后出血的临床效果.方法:选择2021年9月至2022年10月本院收治的102例高危产妇作为研究对象,按简单随机化法分组;对照组(51例)仅使用卡前列素氨丁三醇及麦角新碱干预;研究组(51例)予以卡前列素氨丁三醇及麦角新碱,并放置宫腔球囊压迫止血.评估治疗后疗效,记录两组产妇产后不同时间出血量、第三产程时间及分娩后1分钟Apgar评分,对比两组治疗前后凝血功能相关指标[凝血酶原时间(PT)、凝血酶时间(TT)、活化部分凝血活酶时间(APTT)],统计两组不良反应发生率.结果:研究组总有效率(98.04％)较对照组(84.31％)高(P＜0.05);两组Apgar评分对比无显著差异(P＞0.05);研究组2h、24h出血量较对照组少,第三产程时间较对照组短(P＜0.05);两组治疗后PT、TT、APTT时间均延长(P＜0.05);但研究组治疗后PT、TT、APTT比对照组短(P＜0.05);两组不良反应发生率(5.88％vs 11.76％)相比无统计学差异(P＞0.05).结论:卡前列素氨丁三醇及麦角新碱联合一次性宫腔球囊应用于高危产妇产后出血中效果较佳,可减少出血量,改善凝血功能.
Abstract
Objective:To discuss the effect of carboprost tromethamine,ergometrine and disposable intrauterine balloon in the prevention of postpartum hemorrhage in high-risk pregnant.Methods:102 high-risk pregnant women in our hospital from Sep 2021 to Oct 2022 were selected as the research subjects and grouped according to a simple randomization method.Pregnant in control group(51 cases)received carboprost tromethamine and ergometrine,and pregnant in study group(51 cases)received carboprost tromethamine,ergometrine and disposable intrauterine balloon compression for hemostasis.The therapeutic effect after treatment,amount of postpartum bleeding at different times,third stage of labor time,Apgar score at 1 minute after delivery,coagulation function related indicators[prothrombin time(PT),thrombin time(TT),activated partial thromboplastin time(APTT)]in the two groups were evaluate and recorded.At the same time,the incidence of adverse reactions in the two groups were compared.Result:The total effective rate of the study group(98.04％)was higher than that of the control group(84.31％),with significant difference(P＜0.05).There was no significant difference in Apgar scores between the two groups(P＞0.05);The study group had less bleeding at 2 and 24 hours compared to control group,and the third stage of labor time was shorter than the control group(P＜0.05).After treatment,the PT,TT,and APTT in the study group were shorter than those in control group(P＜0.05).There was no difference in the incidence of adverse reactions between the two groups(P＞0.05).Conclusion:The combination of carboprost tromethamine,ergometrine and disposable intrauterine balloon is more effective in high-risk postpartum hemorrhage,which can reduce bleeding volume and improve coagulation function.
关键词
高危产妇/产后出血/卡前列素氨丁三醇/麦角新碱/一次性宫腔球囊Key words
High risk pregnant/Postpartum hemorrhage/Carboprost tromethamine/Ergoxine/Disposable intr-auterine balloon引用本文复制引用
出版年
2024
NETL
NSTL
万方数据