Current Research Status on Cardiovascular Toxicity of Chemotherapy Drugs in China——Visual Analysis Based on CiteSpace Software
Objective:Based on CiteSpace software,visually analyze the domestic research hotspots,research status and development trends in the field of chemotherapeutic drug cardiotoxicity in the past 10 years.Methods:Using the China Knowledge Network database as the data source,the literatures related to cardiotoxicity of chemotherapeutic drugs collected from January 2013 to April 2023 were searched.With the help of CiteSpace software,visual atlas analysis was carried out on the authors,institutions,keywords and other aspects of the included litera-tures.Results:After screening,557 Chinese literatures were finally included.Through visual analysis of the literatures,it can be seen that the annual trend of publication volume in this field is relatively stable;the author with the largest number of publications is Feng Yanying;the research institutions with more publications are Tianjin University of Traditional Chinese Medicine and School of Traditional Chinese Medicine,Beijing University of Chinese Medicine;The keyword atlas has 312 nodes,1009 links,and 18 clusters."Adriamycin",breast can-cer"and"dexalimine"are the three keywords with the highest frequency of occurrence.The top two keyword clusters with a wide range of topics are #breast cancer and #doxorubicin.The keyword that has appeared frequently in the past five years is"oxidative stress".Conclusion:Domestic research on cardiotoxicity of chemotherapeutic drugs shows an overall fluctuating and increasing trend.All institutions and authors should strengthen exchanges and cooperation and promote the formation of cooperation networks.The research content in this field mainly fo-cuses on breast cancer,doxorubicin and dexalimine.In the future,conducting a large number of cell experiments and animal experiments,clarifying the mechanism of cardiotoxicity of chemotherapeutic drugs,building risk prediction models,increasing clinical research,and ex-ploring diversified treatment options may become research hotspots.
万方数据
