首页|Conductive polymer hydrogel-coated nanopipette sensor with tunable size

Conductive polymer hydrogel-coated nanopipette sensor with tunable size

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Nanopipette-based sensors are one of the most effective tools for detecting nanoparticles, bioparticles, and biomolecules. Quantitative analysis of nanoparticles with different shapes and electrical charges is achieved through measurement of the blockage currents that occur when particles pass through the nanopore. However, typical nanopipette sensors fabricated using a conventional needle-pulling method have a typical pore-diameter limitation of around 100 nm. Herein, we report a novel conductive hydrogel-composited nanopipette sensor with a tunable inner-pore diameter. This is made by electrodepositing poly(3,4-ethylenedioxythiophene) polystyrene sulfonate onto the surface of a nanopipette with a prefabricated sacrificial copper layer. Because of the presence of copper ions, the conductive polymer can stably adhere to the tip of the nanopipette to form a nanopore;when nanoparticles pass through the conductive nanopore, more distinct blocking events are observed. The size of the nanopore can be changed simply by adjusting the electrodeposition time. In this way, suitable nanopores can be obtained for highly sensitive screening of a series of particles with diameters of the order of tens of nanometers.

NanopipetteConductive polymerElectrodepositionNanoparticles

Lin Li、Feng Zhou、Qiannan Xue

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State Key Laboratory of Precision Measuring Technology and Instruments,Tianjin University,Tianjin 300072,China

College of Precision Instruments and Optoelectronics Engineering,Tianjin University,Tianjin 300072,China

国家自然科学基金国家重点研发计划高等学校学科创新引智计划(111计划)Scientific Research Transformation Foundation of Wenzhou Safety(Emergency)Institute of Tianjin University

621741192021YFC3002202B07014

2022

10.1063/10.0016501

纳米技术与精密工程(英文)
中国微米纳米技术学会,天津大学

纳米技术与精密工程(英文)

CSTPCDCSCDEI
影响因子：0.476
ISSN：1672-6030
年,卷(期)：2022.5(4)
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