纳米技术与精密工程(英文)2024,Vol.7Issue(1) :10-17.DOI:10.1063/10.0022239

Experiment on inducing apoptosis of melanoma cells by micro-plasma jet

Hua Li Qihao Shi Yanhua Yang Jinghao Qi Yuhan Zhang Fengyun Wang Xiaoxia Du Wenxiang Xiao
纳米技术与精密工程(英文)2024,Vol.7Issue(1) :10-17.DOI:10.1063/10.0022239

Experiment on inducing apoptosis of melanoma cells by micro-plasma jet

Hua Li 1Qihao Shi 2Yanhua Yang 3Jinghao Qi 2Yuhan Zhang 2Fengyun Wang 2Xiaoxia Du 1Wenxiang Xiao1
扫码查看

作者信息

  • 1. School of Life and Environmental Sciences,GuiLin University of Electronic Technology,Guilin,GuangXi 541004,People's Republic of China;The Guangxi Human Physiological Information Noninvasive Detection Engineering Technology Research Center,Guilin,GuangXi 541004,People's Republic of China
  • 2. School of Life and Environmental Sciences,GuiLin University of Electronic Technology,Guilin,GuangXi 541004,People's Republic of China
  • 3. Guilin URIT MEDICAL Electronic Sales Co.,Ltd.,Guilin,GuangXi 541004,People's Republic of China
  • 折叠

Abstract

As a promising cancer treatment method,cold atmospheric plasma has received widespread attention in recent years.However,previous research has focused more on how to realize and expand the anti-cancer scope of plasma jet.There are also studies on the killing of small-scale cancer cells,but the effects of plasma jet on normal cells and normal cell clusters have been ignored.Therefore,we proposed a 50 pm sized micro-plasma jet device,and used the device to treat melanoma cells(A-375)and human glial cells(HA1800)to evaluate their anti-cancer effects and effects on normal cells.The experimental results show that this kind of micro-plasma jet device can effectively inactivate cancer cells in a short period of time,while having little effect on normal cells.This work provides a certain experimental basis for the application of fine plasma jet to clinically inactivate cancer cells.

Key words

3D cell clusters/Micro-plasma jet/Cancer therapy/Reactive oxygen species/Plasma direct treatment

引用本文复制引用

基金项目

国家自然科学基金(Number 62163009)

国家自然科学基金(61864001)

广西自然科学基金(Number 2021JJD170019)

Foundation of Guangxi Key Laboratory of Automatic Detecting Technology and Instruments(Guilin University of Electronic Techn(Number YQ23103)

广西壮族自治区研究生教育创新计划(YCSW2022277)

广西壮族自治区研究生教育创新计划(2023YCXS184)

Guangxi Major Scientific and Technological Innovation Base(Guilin University of Electronic Technology)(231002-k)

出版年

2024
纳米技术与精密工程(英文)
中国微米纳米技术学会,天津大学

纳米技术与精密工程(英文)

CSTPCDCSCDEI
影响因子:0.476
ISSN:1672-6030
参考文献量35
段落导航相关论文