Cd pollution poses a serious threat to sustainable development of modern agriculture and the quality and safety of agricultural products.The prevention and control of Cd pollution in rice is one of the key tasks in comprehensively promoting rural revitalization,and has become a major ecological and environmental problem that needs to be addressed urgently.Se is one of the essential trace elements for humans and animals,and it can antagonize heavy metals,block the damage of heavy metals to plants,and is known as a"natural antidote to heavy metals".The application of Se fertilizer can alleviate the toxicity of Cd to rice growth and reduce the absorption of Cd by rice.However,its mechanism is still inconclusive.The paper analyzed the harm of Cd to rice and the effect of Se on Cd content in rice,summarized and expounded the alleviating effect of Se on Cd stress in rice at present,so as to formulate corresponding measures to reduce the toxicity of Cd to rice,improve the quality of rice,and ensure people's health.