As the"core chip"of variety cultivation,seed industry innovation and high-quality development of agriculture,crop germplasm resources play an irreplaceable fundamental role in variety cultivation and food security.Based on this,the significance of crop germplasm resources research and the development history and current situation of domestic wheat germplasm resources research are expounded,and the existing problems and development trends are analyzed in order to provide theoretical basis for strengthening the research of wheat germplasm resources and promoting wheat breeding.