The effects of 0.2%EDTA-Cu solution,0.4%EDTA-Zn solution and 0.2%EDTA-Cu+0.4%EDTA-Zn solution on spring wheat growth and yield were studied in order to provide theoretical basis for improving spring wheat yield in Ningxia irrigation area.The results showed that spraying micro-fertilizer on the leaf surface could promote the growth of wheat and increase the yield.The overall performance was 0.2%EDTA-Cu solution>0.4%EDTA-Zn solution>0.2%EDTA-Cu+0.4%EDTA-Zn solution,and the effect of spraying 0.2%EDTA-Cu solution alone was the most obvious.Compared with the control(CK),the number of grains per spike increased by 2.1 grains,the 1000-grain weight increased by 1.90 g(8.05%and 3.51%,respectively),the yield increased by 5.43%,and the content of copper in grains increased by 11.31%.After spraying 0.4%EDTA-Zn solution,the plant functional leaf growth was improved,the center of gravity height was decreased,the plant zinc content was increased by 1.17~3.00 mg·kg-1,the grain zinc content was increased by 8.28%,and the yield was increased by 19.60 kg·667-1·m-2.The yield increased by 11.0 kg·667-1·m-2 after spraying copper and zinc mixture,and the content of copper and zinc in plants and grains increased correspondingly.