Cardioprotective Effect of Pre-infarction Angina with ST Segment Elevation Myocardial Infarction
Objective To investigate the cardioprotective effect of pre-infarction angina(PIA)on the patients with acute ST segment elevation myocardial infarction(STEMI).Methods From January 2020 to December 2020,323 patients with STEMI who underwent emergency percutaneous coronary intervention(PCI)in the General Hospital of Ningxia Medical University were divided into the PIA group(163 cases)and the control group(160 cases).The cardiac troponinⅠ,white blood cell,C-reactive protein,N-terminal pro-B-type natri-uretic peptide(NT-proBNP),myocardial infarction area,cardiac function,coronary artery lesion and TIMI blood flow were detected in all objects.The major adverse cardiovascular events(MACE)in hospital were recorded in the two groups.Results The mean values of cTnⅠ,WBC,CRP,NT-proBNP,myocardial infarction area and no reflow/slow blood flow incidence in PIA group were significantly lower than those in the control group(P all<0.05).The LVEF value in the PIA group was significantly higher than that in the control group(P<0.05).The incidence of MACE during hospitalization was significantly lower than that in the control group(P<0.05).Conclusion PIA plays a cardioprotective role by reducing myocardial injury and myocardial infarction size,decreasing inflammatory reaction,improving left ventricular function and reducing the incidence of no re-flow/slow blood flow,thereby improving the clinical prognosis of STEMI patients.
万方数据
维普
