宁夏医科大学学报2024,Vol.46Issue(2) :170-175.DOI:10.16050/j.cnki.issn1674-6309.2024.02.010

筛区注射甲泼尼龙琥珀酸钠治疗急性期贝尔面瘫疗效观察

Observation on the Therapeutic Effect of Methylprednisolone Sodium Succinate Injection in the Screening Area for Acute Bell Palsy

郑云雪 李国徽 陈佳 陈腾玉
宁夏医科大学学报2024,Vol.46Issue(2) :170-175.DOI:10.16050/j.cnki.issn1674-6309.2024.02.010

筛区注射甲泼尼龙琥珀酸钠治疗急性期贝尔面瘫疗效观察

Observation on the Therapeutic Effect of Methylprednisolone Sodium Succinate Injection in the Screening Area for Acute Bell Palsy

郑云雪 1李国徽 2陈佳 2陈腾玉3
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作者信息

  • 1. 宁夏医科大学中医学院,银川 750004
  • 2. 宁夏医科大学附属银川市中医医院,银川 750001
  • 3. 陕西中医药大学,咸阳 712046
  • 折叠

摘要

目的 观察筛区注射甲泼尼龙琥珀酸钠治疗急性期贝尔面瘫的临床疗效.方法 将急性期贝尔面瘫120 例随机分为两组,筛区注射组 60 例(筛区注射甲泼尼龙琥珀酸钠+普通针刺),口服给药组 60 例(口服泼尼松片+普通针刺),对患者治疗第 0、5、10、15、20、30 天进行临床疗效评价,采用面神经功能评价分级系统(H-B)及面部残疾指数量表(FDI),比较两组治疗前后的临床疗效,并对耳后疼痛持续时长、不良反应发生情况进行统计.结果 筛区注射组有效率为 88.33%,口服激素组为 90.00%,两组比较差异无统计学意义(P>0.05);治疗前后各时间段两组患者H-B评级、FDI评分比较差异均无统计学意义(P均>0.05);治疗前两组患者耳后疼痛开始时间及入院时间差异均无统计学意义(P均>0.05),治疗后,筛区注射组较口服激素组患者耳后疼痛持续时长缩短(P<0.001).结论 筛区注射给药与全身给药均可获得满意疗效;筛区注射给药可缩短耳后疼痛时长;两组均无严重不良反应发生,筛区注射给药方式值得临床推广.

Abstract

Objective To observe.the clinical efficacy of methylprednisolone sodium succinate injection in the screening area in the treatment of Bell palsy in the acute stage.Methods The 120 cases of Bell palsy in the acute stage were randomly divided into 2 groups,60 cases in the sieve injection group(sieve injection of methylprednisolone sodium succinate+ordinary acupuncture),and 60 cases in the oral hormone group(oral prednisone tablets + ordinary acupuncture),and the clinical efficacy of the patients was evaluated on the day0,5,10,15,20 and 30 day of treatment.The facial nerve function evaluation grading system(H-B)and facial disability index scale(FDI)were used to compare the clinical efficacy of the two groups before and after treatment,and the duration of pain behind the ear and the occurrence of adverse reactions were statistical.Re-sults The effective rate was 88.33%in the sieve injection group and 90.00%in the oral hormone group,and there was no significant difference between the two groups(P>0.05);there was no significant difference in H-B rating and FDI score between the two groups in the time period before and after treatment(P all>0.05);there was no significant difference in the onset time and admission time of behind the ear pain in the two groups before treatment(Pall>0.05),and the duration of post-treatment sieve injection group was shorter than that in the oral hormone group(P<0.001).Conclusion Both sieve injection administration and systemic administration can obtain satisfactory efficacy.Sieve injection can significantly shorten the duration of pain behind the ear.There was no incidence of serious adverse reactions in either group,and the sieve injection administration method is worthy of clinical promotion.

关键词

筛区/筛区注射/甲泼尼龙琥珀酸钠/贝尔面瘫/疗效观察

Key words

sieve area/sieve area injection/methylprednisolone sodium succinate/Bell palsy/efficacy observation

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基金项目

宁夏回族自治区重点研发计划(2020BEG03036)

陕西中医药大学校级项目(2021FS14)

出版年

2024
宁夏医科大学学报
宁夏医科大学

宁夏医科大学学报

CSTPCD
影响因子:0.84
ISSN:1674-6309
参考文献量21
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