宁夏医科大学学报2024,Vol.46Issue(3) :245-249.DOI:10.16050/j.cnki.issn1674-6309.2024.03.005

7 112例过敏性鼻炎患者花粉过敏原检测分析

Analysis of Pollen Allergen Test in 7 112 Patients with Allergic Rhinitis

冯博 张银豪 吴惠忠 齐爱 牛照地 孙伟
宁夏医科大学学报2024,Vol.46Issue(3) :245-249.DOI:10.16050/j.cnki.issn1674-6309.2024.03.005

7 112例过敏性鼻炎患者花粉过敏原检测分析

Analysis of Pollen Allergen Test in 7 112 Patients with Allergic Rhinitis

冯博 1张银豪 2吴惠忠 2齐爱 2牛照地 2孙伟2
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作者信息

  • 1. 宁夏医科大学公共卫生学院,银川 750004;宁夏环境因素与慢性病控制重点实验室,银川 750004
  • 2. 宁夏回族自治区疾病预防控制中心,银川 750004
  • 折叠

摘要

目的 了解宁夏地区过敏性鼻炎(allergic rhinitis,AR)患者的花粉过敏原致敏谱,分析不同年龄和性别间阳性致敏原的差异,为AR患者的治疗和预防提供依据.方法 采用皮肤点刺试验(skin prick test,SPT)对2021年12月至2022年12月就诊于宁夏8所监测医院呼吸科、耳鼻喉科和儿科门诊的7 112例AR患者进行花粉过敏原检测,分析检测结果,并探讨检测结果的年龄和性别差异.结果 7 112例AR患者花粉SPT阳性率为68.81%,其中AR患者花粉过敏原阳性率最高的两种花粉为大籽蒿花粉(57.27%)和黄花蒿花粉(41.42%),合并4种及以上花粉过敏原SPT阳性者占35.45%;大籽蒿花粉和黄花蒿花粉致敏级别主要为3~4级;AR患者花粉过敏原SPT阳性率随年龄增长呈现先递增后递减趋势,10~<20岁年龄组花粉过敏原SPT阳性检出率达峰值(79.59%),8种花粉过敏原在不同年龄组的差异均有统计学意义(P均<0.05);不同性别间比较,大籽蒿花粉、葎草花粉、柳树花粉、杨树花粉、家榆花粉、槐树花粉阳性率男性高于女性(P均<0.05).结论 AR患者常合并4种及以上花粉过敏原致敏,10~<20岁年龄组SPT阳性检出率达峰值,大籽蒿花粉和黄花蒿花粉是宁夏地区AR患者最常见的花粉过敏原.

Abstract

Objective To understand the sensitization spectrum of pollen allergens in patients with allergic rhinitis(AR)in Ningxia,and to analyze the differences in positive allergens between different ages and genders,in order to provide a basis for the treatment and prevention of AR patients.Methods A skin prick test(SPT)was used to detect pollen allergens in 7 112 AR patients attending respiratory,otolaryngology and paediatrics outpatient clinics in eight monitoring hospitals in Ningxia from December 2021 to December 2022,to analyse the results of the test and to explore the age and gender differences in the test results.Results The positive rate of pollen SPT in 7 112 AR patients was 68.81%.Among them,the two types of pollen with the highest positive rate of pollen allergens in AR patients were artemisia grandis pollen(57.27%)and artemisia annua pollen(41.42%),and the combination of four or more pollen allergens with SPT positive accounted for 35.45%of the patients.The sensitization level of artemisia grandis pollen and artemisia annua pollen were mainly grade 3 to 4.The positive rate of pollen allergen SPT in AR patients increased first and then decreased with age,and the positive detection rate of pollen allergen SPT in the age group of 10-<20 years reached the peak(79.59%),and the eight pollen allergens were statistically significant in the different age groups(P all<0.05).The positive rates of pollen of artemisia grandis,humulus humilis,willow pollen,poplar pollen,domestic elm pollen,and sophora japonica were higher in males than in females among different genders(P all<0.05).Conclusion AR patients were often sensitized by a combination of 4 or more pollen allergens.The peak detection rate of SPT positive was reached in the age group of 10-<20 years.Artemisia grandis pollen and Artemisia annua pollen were the most common pollen allergens in AR patients in Ningxia region.

关键词

过敏性鼻炎/花粉过敏原/皮肤点刺试验

Key words

allergic rhinitis/pollen allergens/skin prick test

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基金项目

宁夏卫生健康委高层次科技提升项目(2023-NWKYT-015)

出版年

2024
宁夏医科大学学报
宁夏医科大学

宁夏医科大学学报

CSTPCD
影响因子:0.84
ISSN:1674-6309
参考文献量20
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