目的 探讨下肢动脉硬化性疾病无症状高危人群的危险因素及踝肱指数(ankle-brachial index,ABI)的预测价值.方法 选取2020年1月至2022年12月成武县人民医院110例无下肢动脉硬化性疾病症状的高危人群为研究对象,均接受ABI测量,根据ABI将其分为异常组和正常组,对比两组基线资料,并分析影响下肢动脉硬化性疾病无症状高危人群的危险因素及ABI的预测价值.结果 经ABI测量显示,ABI≤0.9共31例,占比28.18％.异常组年龄,有高血压史、糖尿病史、吸烟史占比,C反应蛋白及同型半胱高于正常组,总胆固醇及ABI低于正常组(P均＜0.05).年龄、高血压史、糖尿病史、吸烟史、同型半胱氨酸、ABI是下肢动脉硬化性疾病无症状高危人群的影响因素(P均＜0.05).年龄、同型半胱氨酸、ABI预测下肢动脉硬化性疾病无症状高危人群的曲线下面积(area under curve,AUC)分别为0.959、0.965、0.986,ABI预测的敏感度优于年龄和同型半胱氨酸预测(P均＜0.05).结论 早期检测ABI对下肢动脉硬化性疾病无症状高危人群具有预测作用.
The Predictive Value of Early Detection of Ankle-brachial Index in Asymptomatic High-risk Population of Lower Extremity Arteriosclerosis Disease
Objective To investigate the risk factors and predictive value of ankle-brachial index(ABI)in asymptomatic high-risk population with lower extremity arteriosclerosis disease.Methods 110 high-risk groups without symptoms of lower extremity arteriosclerosis disease in Chengwu County People's Hospital from January 2020 to December 2022 were selected as the study subjects.They all accepted ABI measurement and were divided into abnormal group and normal group according to ABI.The baseline data of the two groups were compared,and the risk factors and predictive value affecting the asymptomatic high-risk groups of lower extremity arteriosclerosis disease were analyzed.Results According to ABI measurement,there were 31 cases with ABI ≤0.9,accounting for 28.18％.The age,history of hypertension,diabetes,smoking,C-reactive protein and homocysteine in the abnormal group were higher than those in the normal group,while total cholesterol and ABI were lower than those in the normal group(P all＜0.05).Age,history of hypertension,history of diabetes,history of smoking,homocysteine,ABI were risk factors for asymptomatic high-risk population of lower extremity arteriosclerosis disease(P all＜0.05).Age,homocysteine and ABI predicted the area under curve(AUC)of asymptomatic high risk population of lower extremity arteriosclerosis disease were 0.959,0.965 and 0.986.The sensitivity of ABI prediction was better than that of age and homocysteine prediction(P all＜0.05).Conclusion Early detection of ABI had a predictive and preventive effect on asymptomatic high-risk groups of lower extremity atherosclerosis disease.
万方数据
维普
