Quantitative Analysis of Macular Microcirculation Changes in Children with Obstructive Sleep Apnea Syndrome Using OCTA
Objective To investigate the effects of optical coherence tomography angiography(OCTA)on the length of blood vessels,blood flow density,and size of the focal avascular zone(FAZ)in the macular region of pediatric obstructive sleep apnea syndrome(OSAS).Methods Fifty-one pediatric patients who visited the Department of Otolaryngology at Ningde Municipal Hospital of Ningde Normal University from January 2020 to December 2021 were collected as experimental group,and 51 normal children were chosen as a control group.After undergoing height,naked eye vision,refractive index,and corrected vision examinations for all patients,pediatric patients would be identified and undergo ophthalmic examinations simultaneously.The differences in superficial capillary vascular length density(VLD),blood perfusion density(VPD),and macular area FAZ between two groups were observed.Results There was no significant difference in VLD1,VLD3 and VLD4 between the two groups(P＞0.05).VLD2 was higher in the experimental group than in the control group(t=-3.334,P=0.01).There was no significant difference in VPD3 and FAZ in the superficial inacula between the two groups(Pall＞0.05).VPD1 and VPD2 of the experimental group were smaller than the control group(P all＜0.001),while VPD4 of the experimental group was larger than the control group(P＜0.001).Conclusion OCTA examination could quantitatively analyze the microcirculation changes in the macular area of children with OSAS,and the microcirculation changes in the macular area of children with OSAS were an early indicator of retinal hypoxia.
万方数据
维普
