Analysis of the Effectiveness of Two Risk Scoring Systems in Gastric Cancer Opportunistic Screening in Wuzhong Area of Ningxia
Objective To compare the efficacy of two risk assessment models in the early screening of gastric cancer in Wuzhong of Ningxia,and to explore an evaluation system that was more suitable for early screening of gastric cancer in this area.Methods A total of 1 085 patients aged 40～69 years who underwent opportunistic screening for gastric cancer in Wuzhong People's Hospital and Yanchi County People's Hospital from May 2022 to May 2023 were included.The risk of gastric cancer was assessed simultaneously according to the"Up-per gastrointestinal cancer risk scoring system"and the"New gastric cancer screening scoring system"devel-oped by Peking University Cancer Research Center,and the screening effects of different scoring systems on early gastric cancer were compared.Results A total of 1 085 eligible subjects were included,including 539 males(49.68％),546 females(50.32％)with an average age of(54.7±7.8)years.The high-risk rate of the Upper gastrointestinal cancer risk scoring system was 14.65％(159/1 085),which was lower than that of the New gastric cancer screening scoring system 32.53％(353/1 085)(x2=73.51,P＜0.001).The positive rates of the Upper gastrointestinal cancer risk scoring system and the New gastric cancer screening scoring system were 4.40％and 4.25％,respectively,and the overall consistency rate was 74.93％(Kappa value=0.334,P＜0.001).There was no significant difference in the distribution of gastric cancer(x2=3.00,P=0.083).The sensitivity(38.89％),negative predictive value(98.81％)and diagnostic odds ratio(3.83)and score under the ROC curve(0.623,95％CI:0.478-0.768)of the Upper gastrointestinal cancer risk scoring system were all lower than those of the New gastric cancer screening scoring system[83.33％,99.59％,10.78 and 0.758(95％CI:0.656-0.861)].The specificity(85.75％)and positive predictive value(4.40％)were higher than those of the New gastric cancer screening scoring system(68.32％,4.25％).The Kappa value of the two risk assessment models was equal to 0.05.Conclusion The two risk scoring systems had certain predictive ability and advantages for the early di-agnosis of gastric cancer in the opportunistic screening of gastric cancer in the population of Wuzhong,Ningxia.In terms of screening accuracy,the New gastric cancer screening scoring system was superior to the Upper gas-trointestinal cancer risk scoring system,but in terms of screening benefits,the upper gastrointestinal cancer risk scoring system was superior to the New gastric cancer screening scoring system.
万方数据
维普
