Analysis of Pathogen Distribution and Drug Resistance in Single-center PICU from 2019 to 2021
Objective To explore the isolation of pathogenic bacteria and drug susceptibility in single-center pediatric intensive care unit(PICU)from 2019 to 2021,and to provide a laboratory basis for the rational use of antimicrobial drugs and guide clinical practice.Methods Pathogen specimen culture and drug sensitivity re-sults of infected patients treated in PICU at General Hospital of Ningxia Medical University from January 1,2019 to December 30,2021 were retrospectively analyzed.Results There were 172 cases in 2019,127 cases in 2020,and 157 cases in 2021 with bacterial culture and drug sensitivity results.Respiratory infections ranked first,with the first pathogenic bacterium being Haemophilus influenzae.There was no significant resis-tance to third-generation cephalosporins,azithromycin,and quinolones.The resistance rate of Staphylococcus aureus to penicillin was 92.8％,and no resistance to vancomycin or linezolid was found.Conclusion The common infection sites in children are still mainly respiratory tract,and the common pathogenic bacteria are still mainly Gram-negative so targeted clinical treatment should he conducted according to the results of drug sensi-tivity.
万方数据
维普
